WHO SMART Guidelines - HIV
0.4.3 - ci-build

WHO SMART Guidelines - HIV - Local Development build (v0.4.3) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

ValueSet: WHO HIV clinical stage condition or symptom ValueSet (Experimental)

Official URL: http://smart.who.int/hiv/ValueSet/HIV.D.DE289 Version: 0.4.3
Active as of 2025-03-14 Computable Name: HIVDDE289

Value set of new or recurrent clinical events used to categorize HIV disease severity based at baseline and follow up

References

Logical Definition (CLD)

Generated Narrative: ValueSet HIV.D.DE289

  • Include these codes as defined in http://smart.who.int/hiv/CodeSystem/HIVConcepts
    CodeDisplayDefinition
    HIV.D.DE290AsymptomaticNo HIV-related symptoms reported and no clinical signs on examination
    HIV.D.DE291Persistent generalized lymphadenopathyPersistent enlarged lymph nodes >1 cm at two or more non-contiguous sites (excluding inguinal) without known cause
    HIV.D.DE292Moderate unexplained weight lossModerate unexplained weight loss (<10% of presumed or measured body weight)
    HIV.D.DE293Recurrent respiratory tract infectionsClient's symptoms include recurrent respiratory tract infections including sinusitis, tonsillitis, otitis media or pharyngitis
    HIV.D.DE294Unexplained persistent hepatosplenomegalyClient's symptoms include unexplained persistent hepatosplenomegaly
    HIV.D.DE295Herpes zosterClient's symptoms include herpes zoster
    HIV.D.DE296Angular cheilitisClient's symptoms include angular cheilitis
    HIV.D.DE297Linear gingival erythemaClient's symptoms include linear gingival erythema
    HIV.D.DE298Recurrent oral ulcerationClient's symptoms include recurrent oral ulceration
    HIV.D.DE299Papular pruritic eruptionClient's symptoms include papular pruritic eruption
    HIV.D.DE300Fungal nail infectionsClient's symptoms include fungal nail infections
    HIV.D.DE301Seborrhoeic dermatitisClient's symptoms include seborrhoeic dermatitis
    HIV.D.DE302Extensive wart virus infectionClient's symptoms include extensive wart virus infection
    HIV.D.DE303Extensive molluscum contagiosumClient's symptoms include extensive molluscum contagiosum
    HIV.D.DE304Unexplained persistent parotid enlargementClient's symptoms include unexplained persistent parotid enlargement
    HIV.D.DE305Unexplained severe weight loss in adultsUnexplained severe weight loss (>10% of presumed or measured body weight)
    HIV.D.DE306Unexplained moderate malnutrition not adequately responding to standard therapyDefined as weight-for-height < - 2 z-score or mid-upper arm circumference 115 mm to <125 mm. For children younger than five years of age: stunting is defined as severe acute malnutrition - either weight for height < -3 z-score or mid-upper arm circumference <115 mm or the presence of oedema.
    HIV.D.DE307Unexplained chronic diarrhoea for longer than 1 monthClient's symptoms include unexplained chronic diarrhoea for longer than 1 month
    HIV.D.DE308Unexplained persistent diarrhoea (14 days or more)Client's symptoms include unexplained persistent diarrhoea (14 days or more)
    HIV.D.DE309Unexplained persistent fever (above 37.5 C, intermittent or constant, for longer than one 1 month)Client's symptoms include unexplained persistent fever (above 37.5 C, intermittent or constant, for longer than one 1 month)
    HIV.D.DE310Persistent oral candidiasisClient's symptoms include persistent oral candidiasis
    HIV.D.DE311Oral hairy leukoplakiaClient has fine white small linear or corrugated lesions on lateral borders of the tongue that do not scrape off
    HIV.D.DE312Pulmonary TBClient's symptoms include pulmonary TB
    HIV.D.DE313Lymph node TBClient's symptoms include lymph node TB
    HIV.D.DE314Severe bacterial infections (such as pneumonia, empyema, pyomyositis, bone or joint infection, meningitis, bacteraemia)Client's symptoms include severe bacterial infections (such as pneumonia, empyema, pyomyositis, bone or joint infection, meningitis, bacteraemia)
    HIV.D.DE315Severe recurrent bacterial pneumoniaClient's symptoms include severe recurrent bacterial pneumonia
    HIV.D.DE316Acute necrotizing ulcerative stomatitisClient's symptoms include acute necrotizing ulcerative stomatitis
    HIV.D.DE317Acute necrotizing ulcerative gingivitisClient's symptoms include acute necrotizing ulcerative gingivitis
    HIV.D.DE318Acute necrotizing ulcerative periodontitisClient's symptoms include acute necrotizing ulcerative periodontitis
    HIV.D.DE319Unexplained anaemia (<8 g/dL)Client's symptoms include unexplained anaemia (<8 g/dL)
    HIV.D.DE320Neutropaenia (<0.5 x 10^9/L)Client's symptoms include neutropaenia (<0.5 x 10^9/L)
    HIV.D.DE321Chronic thrombocytopaenia (<50 x 10^9/L)Client's symptoms include chronic thrombocytopaenia (<50 x 10^9/L)
    HIV.D.DE322Symptomatic lymphoid interstitial pneumonitisClient's symptoms include symptomatic lymphoid interstitial pneumonitis
    HIV.D.DE323Chronic HIV-associated lung disease, including bronchiectasisClient's symptoms include chronic HIV-associated lung disease, including bronchiectasis
    HIV.D.DE324HIV wasting syndromeUnexplained involuntary weight loss (>10% baseline body weight), with obvious wasting or body mass index <18.5; PLUS EITHER unexplained chronic reported for longer than one month; OR reports of fever or night sweats for more than one month without other cause and lack of response to antibiotics or antimalarial agents; malaria must be excluded in malarious areas.
    HIV.D.DE325Unexplained severe wasting not responding to standard therapyClient has unexplained severe wasting not responding to standard therapy . For under 5 years old, defined as weight-for-height < -3 z-score
    HIV.D.DE326Unexplained stunting not responding to standard therapyClient has unexplained stunting not responding to standard therapy . For under 5 years old, defined as length-for- age/height-for-age < -2 z-score
    HIV.D.DE327Unexplained severe malnutrition not responding to standard therapyClient has unexplained severe malnutrition not responding to standard therapy . For under 5 years old, weight for height < -3 z-score or mid-upper arm circumference <115 mm or the presence of oedema
    HIV.D.DE328Pneumocystis (jirovecii) pneumoniaClient's symptoms include pneumocystis (jirovecii) pneumonia
    HIV.D.DE329Recurrent severe bacterial pneumoniaClient's symptoms include recurrent severe bacterial pneumonia
    HIV.D.DE330Recurrent severe bacterial infections (such as empyema, pyomyositis, bone or joint infection, meningitis, but excluding pneumonia)Client's symptoms include recurrent severe bacterial infections (such as empyema, pyomyositis, bone or joint infection, meningitis, but excluding pneumonia)
    HIV.D.DE331EmpyemaClient's symptoms include recurrent empyema
    HIV.D.DE332PyomyositisClient's symptoms include recurrent pyomyositis
    HIV.D.DE333Bone or joint infectionClient's symptoms include recurrent bone or joint infections
    HIV.D.DE334MeningitisClient's symptoms include recurrent meningitis
    HIV.D.DE335Chronic herpes simplex infection (orolabial or cutaneous of more than 1 month duration or visceral at any site)Client's symptoms include chronic herpes simplex infection (orolabial or cutaneous of more than 1 month duration or visceral at any site)
    HIV.D.DE336Chronic herpes simplex infection (orolabial, genital or anorectal of more than 1 month in duration or visceral at any site)Client's symptoms include chronic herpes simplex infection (orolabial, genital or anorectal of more than one month in duration or visceral at any site)
    HIV.D.DE337Oesophageal candidiasis (or candidiasis of trachea, bronchi or lungs)Client's symptoms include oesophageal candidiasis (or candidiasis of trachea, bronchi or lungs)
    HIV.D.DE338Extrapulmonary TBClient's symptoms include extrapulmonary tuberculosis
    HIV.D.DE339Kaposi sarcomaClient's symptoms include Kaposi sarcoma
    HIV.D.DE340Cytomegalovirus infection (retinitis or infection of other organs)Client's symptoms include cytomegalovirus infection (retinitis or infection of other organs)
    HIV.D.DE341Central nervous system toxoplasmosisClient's symptoms include central nervous system toxoplasmosis
    HIV.D.DE342HIV encephalopathyClient's symptoms include HIV encephalopathy
    HIV.D.DE343Extrapulmonary cryptococcosis, including meningitisClient's symptoms include extrapulmonary cryptococcosis, including meningitis
    HIV.D.DE344Disseminated nontuberculous mycobacterial infectionClient's symptoms include disseminated nontuberculous mycobacterial infection
    HIV.D.DE345Progressive multifocal leukoencephalopathyClient's symptoms include progressive multifocal leukoencephalopathy
    HIV.D.DE346Chronic cryptosporidiosisClient's symptoms include chronic cryptosporidiosis
    HIV.D.DE347Chronic cryptosporidiosis (with diarrhoea)Client's symptoms include chronic cryptosporidiosis (with diarrhoea)
    HIV.D.DE348Chronic isosporiasisClient's symptoms include chronic isosporiasis
    HIV.D.DE349Disseminated mycosis (extrapulmonary histoplasmosis, coccidioidomycosis)Client's symptoms include disseminated mycosis (extrapulmonary histoplasmosis, coccidioidomycosis)
    HIV.D.DE350Disseminated endemic mycosis (extrapulmonary histoplasmosis, coccidioidomycosis, penicilliosis)Client's symptoms include disseminated endemic mycosis (extrapulmonary histoplasmosis, coccidioidomycosis, penicilliosis)
    HIV.D.DE351Cerebral lymphomaClient's symptoms include cerebral lymphoma
    HIV.D.DE352B-cell non-Hodgkin lymphomaClient's symptoms include b-cell non-Hodgkin lymphoma
    HIV.D.DE353HIV-associated nephropathy or cardiomyopathyClient's symptoms include HIV- associated nephropathy or cardiomyopathy
    HIV.D.DE354Recurrent septicaemia (including nontyphoidal Salmonella)Client's symptoms include recurrent bacteraemia (septicaemia) (including nontyphoidal salmonella)
    HIV.D.DE355Invasive cervical carcinomaClient's symptoms include invasive cervical carcinoma
    HIV.D.DE356Atypical disseminated leishmaniasisClient's symptoms include atypical disseminated leishmaniasis
    HIV.D.DE357NeutropeniaClient's symptoms include neutropenia, an abnormally low count of a type of white blood cell (neutrophils)

 

Expansion

ValueSet

Expansion performed internally based on codesystem WHO SMART HIV Concepts CodeSystem v0.4.3 (CodeSystem)

This value set contains 68 concepts

CodeSystemDisplay (en-US)Definition
  HIV.D.DE290http://smart.who.int/hiv/CodeSystem/HIVConcepts

No HIV-related symptoms reported and no clinical signs on examination

  HIV.D.DE291http://smart.who.int/hiv/CodeSystem/HIVConcepts

Persistent enlarged lymph nodes >1 cm at two or more non-contiguous sites (excluding inguinal) without known cause

  HIV.D.DE292http://smart.who.int/hiv/CodeSystem/HIVConcepts

Moderate unexplained weight loss (<10% of presumed or measured body weight)

  HIV.D.DE293http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent respiratory tract infections including sinusitis, tonsillitis, otitis media or pharyngitis

  HIV.D.DE294http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include unexplained persistent hepatosplenomegaly

  HIV.D.DE295http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include herpes zoster

  HIV.D.DE296http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include angular cheilitis

  HIV.D.DE297http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include linear gingival erythema

  HIV.D.DE298http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent oral ulceration

  HIV.D.DE299http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include papular pruritic eruption

  HIV.D.DE300http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include fungal nail infections

  HIV.D.DE301http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include seborrhoeic dermatitis

  HIV.D.DE302http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include extensive wart virus infection

  HIV.D.DE303http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include extensive molluscum contagiosum

  HIV.D.DE304http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include unexplained persistent parotid enlargement

  HIV.D.DE305http://smart.who.int/hiv/CodeSystem/HIVConcepts

Unexplained severe weight loss (>10% of presumed or measured body weight)

  HIV.D.DE306http://smart.who.int/hiv/CodeSystem/HIVConcepts

Defined as weight-for-height < - 2 z-score or mid-upper arm circumference 115 mm to <125 mm. For children younger than five years of age: stunting is defined as severe acute malnutrition - either weight for height < -3 z-score or mid-upper arm circumference <115 mm or the presence of oedema.

  HIV.D.DE307http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include unexplained chronic diarrhoea for longer than 1 month

  HIV.D.DE308http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include unexplained persistent diarrhoea (14 days or more)

  HIV.D.DE309http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include unexplained persistent fever (above 37.5 C, intermittent or constant, for longer than one 1 month)

  HIV.D.DE310http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include persistent oral candidiasis

  HIV.D.DE311http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client has fine white small linear or corrugated lesions on lateral borders of the tongue that do not scrape off

  HIV.D.DE312http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include pulmonary TB

  HIV.D.DE313http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include lymph node TB

  HIV.D.DE314http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include severe bacterial infections (such as pneumonia, empyema, pyomyositis, bone or joint infection, meningitis, bacteraemia)

  HIV.D.DE315http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include severe recurrent bacterial pneumonia

  HIV.D.DE316http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include acute necrotizing ulcerative stomatitis

  HIV.D.DE317http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include acute necrotizing ulcerative gingivitis

  HIV.D.DE318http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include acute necrotizing ulcerative periodontitis

  HIV.D.DE319http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include unexplained anaemia (<8 g/dL)

  HIV.D.DE320http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include neutropaenia (<0.5 x 10^9/L)

  HIV.D.DE321http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include chronic thrombocytopaenia (<50 x 10^9/L)

  HIV.D.DE322http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include symptomatic lymphoid interstitial pneumonitis

  HIV.D.DE323http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include chronic HIV-associated lung disease, including bronchiectasis

  HIV.D.DE324http://smart.who.int/hiv/CodeSystem/HIVConcepts

Unexplained involuntary weight loss (>10% baseline body weight), with obvious wasting or body mass index <18.5; PLUS EITHER unexplained chronic reported for longer than one month; OR reports of fever or night sweats for more than one month without other cause and lack of response to antibiotics or antimalarial agents; malaria must be excluded in malarious areas.

  HIV.D.DE325http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client has unexplained severe wasting not responding to standard therapy . For under 5 years old, defined as weight-for-height < -3 z-score

  HIV.D.DE326http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client has unexplained stunting not responding to standard therapy . For under 5 years old, defined as length-for- age/height-for-age < -2 z-score

  HIV.D.DE327http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client has unexplained severe malnutrition not responding to standard therapy . For under 5 years old, weight for height < -3 z-score or mid-upper arm circumference <115 mm or the presence of oedema

  HIV.D.DE328http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include pneumocystis (jirovecii) pneumonia

  HIV.D.DE329http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent severe bacterial pneumonia

  HIV.D.DE330http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent severe bacterial infections (such as empyema, pyomyositis, bone or joint infection, meningitis, but excluding pneumonia)

  HIV.D.DE331http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent empyema

  HIV.D.DE332http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent pyomyositis

  HIV.D.DE333http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent bone or joint infections

  HIV.D.DE334http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent meningitis

  HIV.D.DE335http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include chronic herpes simplex infection (orolabial or cutaneous of more than 1 month duration or visceral at any site)

  HIV.D.DE336http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include chronic herpes simplex infection (orolabial, genital or anorectal of more than one month in duration or visceral at any site)

  HIV.D.DE337http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include oesophageal candidiasis (or candidiasis of trachea, bronchi or lungs)

  HIV.D.DE338http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include extrapulmonary tuberculosis

  HIV.D.DE339http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include Kaposi sarcoma

  HIV.D.DE340http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include cytomegalovirus infection (retinitis or infection of other organs)

  HIV.D.DE341http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include central nervous system toxoplasmosis

  HIV.D.DE342http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include HIV encephalopathy

  HIV.D.DE343http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include extrapulmonary cryptococcosis, including meningitis

  HIV.D.DE344http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include disseminated nontuberculous mycobacterial infection

  HIV.D.DE345http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include progressive multifocal leukoencephalopathy

  HIV.D.DE346http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include chronic cryptosporidiosis

  HIV.D.DE347http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include chronic cryptosporidiosis (with diarrhoea)

  HIV.D.DE348http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include chronic isosporiasis

  HIV.D.DE349http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include disseminated mycosis (extrapulmonary histoplasmosis, coccidioidomycosis)

  HIV.D.DE350http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include disseminated endemic mycosis (extrapulmonary histoplasmosis, coccidioidomycosis, penicilliosis)

  HIV.D.DE351http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include cerebral lymphoma

  HIV.D.DE352http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include b-cell non-Hodgkin lymphoma

  HIV.D.DE353http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include HIV- associated nephropathy or cardiomyopathy

  HIV.D.DE354http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include recurrent bacteraemia (septicaemia) (including nontyphoidal salmonella)

  HIV.D.DE355http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include invasive cervical carcinoma

  HIV.D.DE356http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include atypical disseminated leishmaniasis

  HIV.D.DE357http://smart.who.int/hiv/CodeSystem/HIVConcepts

Client's symptoms include neutropenia, an abnormally low count of a type of white blood cell (neutrophils)


Explanation of the columns that may appear on this page:

Level A few code lists that FHIR defines are hierarchical - each code is assigned a level. In this scheme, some codes are under other codes, and imply that the code they are under also applies
System The source of the definition of the code (when the value set draws in codes defined elsewhere)
Code The code (used as the code in the resource instance)
Display The display (used in the display element of a Coding). If there is no display, implementers should not simply display the code, but map the concept into their application
Definition An explanation of the meaning of the concept
Comments Additional notes about how to use the code