WHO Immunization Implementation Guide
1.0.0 - release
WHO Immunization Implementation Guide
1.0.0 - release
WHO Immunization Implementation Guide, published by WHO. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/WorldHealthOrganization/smart-immunizations/tree/132/merge and changes regularly. See the Directory of published versions
| Draft as of 2026-03-31 |
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"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n<div>\n <table class=\"grid dict\">\n \n <tr>\n <th scope=\"row\"><b>Id: </b></th>\n <td style=\"padding-left: 4px;\">IMMZD2DTTyphoidTCV</td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Url: </b></th>\n <td style=\"padding-left: 4px;\"><a href=\"PlanDefinition-IMMZD2DTTyphoidTCV.html\">IMMZ.D2.DT.Typhoid.TCV</a></td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Version: </b></th>\n <td style=\"padding-left: 4px;\">1.0.0</td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Title: </b></th>\n <td style=\"padding-left: 4px;\">IMMZ.D2.DT.Typhoid.TCV</td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Status: </b></th>\n <td style=\"padding-left: 4px;\">draft</td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Type: </b></th>\n <td style=\"padding-left: 4px;\">\n \n \n \n <p style=\"margin-bottom: 5px;\">\n <b>system: </b> <span><a href=\"http://terminology.hl7.org/7.1.0/CodeSystem-plan-definition-type.html\">http://terminology.hl7.org/CodeSystem/plan-definition-type</a></span>\n </p>\n \n \n <p style=\"margin-bottom: 5px;\">\n <b>code: </b> <span>eca-rule</span>\n </p>\n \n \n \n \n \n </td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Date: </b></th>\n <td style=\"padding-left: 4px;\">2026-03-31 13:54:17+0000</td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Publisher: </b></th>\n <td style=\"padding-left: 4px;\">WHO</td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Description: </b></th>\n <td style=\"padding-left: 4px;\"><div><p>IMMZ.D2.DT.Typhoid.TCV\nTyphoid conjugate vaccine (TCV) schedule</p>\n</div></td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Knowledge Capability: </b></th>\n <td style=\"padding-left: 4px;\">\n \n computable \n </td>\n </tr>\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Related Artifacts: </b></th>\n <td style=\"padding-left: 4px;\">\n \n \n <p><b>References</b></p>\n <ul>\n \n <li><div><p>WHO recommendations for routine immunization - summary tables (January 2025)</p>\n</div><br/><a href=\"null\"/></li>\n \n </ul>\n \n \n \n \n \n \n </td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Libraries: </b></th>\n <td style=\"padding-left: 4px;\">\n <table class=\"grid-dict\">\n \n <tr>\n <td><a href=\"Library-IMMZD2DTTyphoidTCVLogic.html\">IMMZD2DTTyphoidTCVLogic</a></td>\n </tr>\n \n </table>\n </td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Actions: </b></th>\n <td style=\"padding-left: 4px;\">\n <table class=\"grid-dict\">\n \n <tr>\n <td>\n \n <b> Determine if the client is due for Typhoid.:</b> Determine if the client is due for Typhoid vaccine according to the national immunization protocol.\nTyphoid conjugate vaccine (TCV) schedule\n \n <br/>\n \n \n <b>If:</b>\n \n <i>Applicability:</i>\n \n Client is due for Typhoid vaccination\n \n <i>(Client is due for Typhoid vaccination)</i>\n <br/>\n \n \n \n \n <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTMR.html\">IMMZD2DTMR</a><br/>\n \n <i>Dynamic Values:</i><br/>\n \n status: <i>('draft')</i>\n <br/>\n \n intent: <i>('proposal')</i>\n <br/>\n \n medication: <i>(Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE21', display: 'Typhoid vaccines' } }, display: 'Typhoid vaccines' })</i>\n <br/>\n \n \n \n \n </td>\n </tr>\n \n <tr>\n <td>\n \n <b> Check for Guidance for the patient regarding IMMZ.D2.DT.Typhoid.TCV.:</b> Show Guidance for the patient regarding IMMZ.D2.DT.Typhoid.TCV.\n \n <br/>\n \n \n <b>If:</b>\n \n <i>Applicability:</i>\n \n Has Guidance\n \n <i>(Has Guidance)</i>\n <br/>\n \n \n \n \n <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n \n <i>Dynamic Values:</i><br/>\n \n status: <i>('active')</i>\n <br/>\n \n payload.contentString: <i>(Guidance)</i>\n <br/>\n \n category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n <br/>\n \n priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n <br/>\n \n \n \n \n </td>\n </tr>\n \n </table>\n </td>\n </tr>\n \n </table>\n</div>\n</div>"
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{
"url" : "statement",
"valueString" : "define function ToBoolean(value boolean): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 25
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "WHOCommon"
},
{
"url" : "name",
"valueString" : "toInterval"
},
{
"url" : "statement",
"valueString" : "/*\nFrom FHIRCommon 4.1.0:\n*/\n\n/*\n@description: Normalizes a value that is a choice of timing-valued types to an equivalent interval\n@comment: Normalizes a choice type of FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instance, FHIR.string, FHIR.Age, or FHIR.Range types\nto an equivalent interval. This selection of choice types is a superset of the majority of choice types that are used as possible\nrepresentations for timing-valued elements in FHIR, allowing this function to be used across any resource.\n\nThe input can be provided as a dateTime, Period, Timing, instant, string, Age, or Range.\nThe intent of this function is to provide a clear and concise mechanism to treat single\nelements that have multiple possible representations as intervals so that logic doesn't have to account\nfor the variability. More complex calculations (such as medication request period or dispense period\ncalculation) need specific guidance and consideration. That guidance may make use of this function, but\nthe focus of this function is on single element calculations where the semantics are unambiguous.\nIf the input is a dateTime, the result a DateTime Interval beginning and ending on that dateTime.\nIf the input is a Period, the result is a DateTime Interval.\nIf the input is a Timing, an error is raised indicating a single interval cannot be computed from a Timing.\nIf the input is an instant, the result is a DateTime Interval beginning and ending on that instant.\nIf the input is a string, an error is raised indicating a single interval cannot be computed from a string.\nIf the input is an Age, the result is a DateTime Interval beginning when the patient was the given Age,\nand ending immediately prior to when the patient was the given Age plus one year.\nIf the input is a Range, the result is a DateTime Interval beginning when the patient was the Age given\nby the low end of the Range, and ending immediately prior to when the patient was the Age given by the\nhigh end of the Range plus one year.\n\nNOTE: Due to the\ncomplexity of determining a single interval from a Timing or String type, this function will throw a run-time exception if it is used\nwith a Timing or String.\n*/\ndefine fluent function toInterval(choice Choice<FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instant, FHIR.string, FHIR.Age, FHIR.Range>):\n case\n when choice is FHIR.dateTime then\n Interval[FHIRHelpers.ToDateTime(choice as FHIR.dateTime), FHIRHelpers.ToDateTime(choice as FHIR.dateTime)]\n when choice is FHIR.Period then\n FHIRHelpers.ToInterval(choice as FHIR.Period)\n when choice is FHIR.instant then\n Interval[FHIRHelpers.ToDateTime(choice as FHIR.instant), FHIRHelpers.ToDateTime(choice as FHIR.instant)]\n when choice is FHIR.Age then\n Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age),\n FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age) + 1 year)\n when choice is FHIR.Range then\n Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).low),\n FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).high) + 1 year)\n when choice is FHIR.Timing then\n Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a Timing value is not supported')\n when choice is FHIR.string then\n Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a String value is not supported')\n else\n null as Interval<DateTime>\n end"
},
{
"url" : "displaySequence",
"valueInteger" : 26
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToDateTime"
},
{
"url" : "statement",
"valueString" : "define function ToDateTime(value dateTime): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 27
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToInterval"
},
{
"url" : "statement",
"valueString" : "define function ToInterval(period FHIR.Period):\n if period is null then\n null\n else\n if period.\"start\" is null then\n Interval(period.\"start\".value, period.\"end\".value]\n else\n Interval[period.\"start\".value, period.\"end\".value]"
},
{
"url" : "displaySequence",
"valueInteger" : 28
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToDateTime"
},
{
"url" : "statement",
"valueString" : "define function ToDateTime(value instant): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 29
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToDate"
},
{
"url" : "statement",
"valueString" : "define function ToDate(value date): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 30
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToQuantity"
},
{
"url" : "statement",
"valueString" : "define function ToQuantity(quantity FHIR.Quantity):\n case\n when quantity is null then null\n when quantity.value is null then null\n when quantity.comparator is not null then\n Message(null, true, 'FHIRHelpers.ToQuantity.ComparatorQuantityNotSupported', 'Error', 'FHIR Quantity value has a comparator and cannot be converted to a System.Quantity value.')\n when quantity.system is null or quantity.system.value = 'http://unitsofmeasure.org'\n or quantity.system.value = 'http://hl7.org/fhirpath/CodeSystem/calendar-units' then\n System.Quantity { value: quantity.value.value, unit: ToCalendarUnit(Coalesce(quantity.code.value, quantity.unit.value, '1')) }\n else\n Message(null, true, 'FHIRHelpers.ToQuantity.InvalidFHIRQuantity', 'Error', 'Invalid FHIR Quantity code: ' & quantity.unit.value & ' (' & quantity.system.value & '|' & quantity.code.value & ')')\n end"
},
{
"url" : "displaySequence",
"valueInteger" : 31
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToCalendarUnit"
},
{
"url" : "statement",
"valueString" : "define function ToCalendarUnit(unit System.String):\n case unit\n when 'ms' then 'millisecond'\n when 's' then 'second'\n when 'min' then 'minute'\n when 'h' then 'hour'\n when 'd' then 'day'\n when 'wk' then 'week'\n when 'mo' then 'month'\n when 'a' then 'year'\n else unit\n end"
},
{
"url" : "displaySequence",
"valueInteger" : 32
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToConcept"
},
{
"url" : "statement",
"valueString" : "define function ToConcept(concept FHIR.CodeableConcept):\n if concept is null then\n null\n else\n System.Concept {\n codes: concept.coding C return ToCode(C),\n display: concept.text.value\n }"
},
{
"url" : "displaySequence",
"valueInteger" : 33
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToCode"
},
{
"url" : "statement",
"valueString" : "define function ToCode(coding FHIR.Coding):\n if coding is null then\n null\n else\n System.Code {\n code: coding.code.value,\n system: coding.system.value,\n version: coding.version.value,\n display: coding.display.value\n }"
},
{
"url" : "displaySequence",
"valueInteger" : 34
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
}
],
"name" : "EffectiveDataRequirements",
"status" : "active",
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/library-type",
"code" : "module-definition"
}
]
},
"relatedArtifact" : [
{
"type" : "depends-on",
"display" : "FHIR model information",
"resource" : "http://fhir.org/guides/cqf/common/Library/FHIR-ModelInfo|4.0.1"
},
{
"type" : "depends-on",
"display" : "Library Encounter",
"resource" : "http://smart.who.int/immunizations/Library/IMMZD2DTTyphoidEncounterElements"
},
{
"type" : "depends-on",
"display" : "Library Encounter",
"resource" : "http://smart.who.int/immunizations/Library/IMMZEncounterElements"
},
{
"type" : "depends-on",
"display" : "Library Common",
"resource" : "http://smart.who.int/immunizations/Library/IMMZCommon"
},
{
"type" : "depends-on",
"display" : "Library FHIRHelpers",
"resource" : "http://fhir.org/guides/cqf/common/Library/FHIRHelpers|4.0.1"
},
{
"type" : "depends-on",
"display" : "Library Elements",
"resource" : "http://smart.who.int/immunizations/Library/IMMZElements"
},
{
"type" : "depends-on",
"display" : "Library WC",
"resource" : "http://smart.who.int/immunizations/Library/WHOCommon"
},
{
"type" : "depends-on",
"display" : "Library Concepts",
"resource" : "http://smart.who.int/immunizations/Library/IMMZConcepts"
},
{
"type" : "depends-on",
"display" : "Value set Typhoid vaccines",
"resource" : "http://smart.who.int/immunizations/ValueSet/IMMZ.Z.DE21"
}
],
"parameter" : [
{
"name" : "Today",
"use" : "in",
"min" : 0,
"max" : "1",
"type" : "date"
},
{
"name" : "Guidance",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "string"
},
{
"name" : "Has Guidance",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "boolean"
},
{
"name" : "Client is due for Typhoid vaccination",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "boolean"
}
],
"dataRequirement" : [
{
"type" : "Patient",
"profile" : [
🔗 "http://hl7.org/fhir/StructureDefinition/Patient"
],
"mustSupport" : [
"birthDate"
]
},
{
"type" : "Immunization",
"profile" : [
🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
],
"mustSupport" : [
"status",
"isSubpotent",
"protocolApplied",
"occurrence"
],
"codeFilter" : [
{
"path" : "status",
"code" : [
{
"code" : "completed"
}
]
}
]
},
{
"type" : "Immunization",
"profile" : [
🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
],
"mustSupport" : [
"status",
"isSubpotent",
"occurrence",
"vaccineCode",
"protocolApplied"
],
"codeFilter" : [
{
"path" : "status",
"code" : [
{
"code" : "completed"
}
]
},
{
"path" : "vaccineCode",
"valueSet" : "http://smart.who.int/immunizations/ValueSet/IMMZ.Z.DE21"
}
]
}
]
}
],
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
"valueCode" : "computable"
},
{
"url" : "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-effectiveDataRequirements",
"valueCanonical" : "#effective-data-requirements"
}
],
"url" : "http://smart.who.int/immunizations/PlanDefinition/IMMZD2DTTyphoidTCV",
"version" : "1.0.0",
"name" : "IMMZD2DTTyphoidTCV",
"title" : "IMMZ.D2.DT.Typhoid.TCV",
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
"code" : "eca-rule"
}
]
},
"status" : "draft",
"experimental" : false,
"date" : "2026-03-31T13:54:17+00:00",
"publisher" : "WHO",
"contact" : [
{
"name" : "WHO",
"telecom" : [
{
"system" : "url",
"value" : "http://who.int"
}
]
}
],
"description" : "IMMZ.D2.DT.Typhoid.TCV\nTyphoid conjugate vaccine (TCV) schedule",
"relatedArtifact" : [
{
"type" : "citation",
"citation" : "WHO recommendations for routine immunization - summary tables (January 2025)"
}
],
"library" : [
🔗 "http://smart.who.int/immunizations/Library/IMMZD2DTTyphoidTCVLogic"
],
"action" : [
{
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-rationale",
"valueMarkdown" : "WHO recommends the TCV as a 0.5 mL single dose for infants and children from 6 months of \n age and in adults up to 45 years in typhoid endemic regions."
}
],
"title" : "Determine if the client is due for Typhoid.",
"description" : "Determine if the client is due for Typhoid vaccine according to the national immunization protocol.\nTyphoid conjugate vaccine (TCV) schedule",
"condition" : [
{
"kind" : "applicability",
"expression" : {
"description" : "Client is due for Typhoid vaccination",
"language" : "text/cql-identifier",
"expression" : "Client is due for Typhoid vaccination"
}
}
],
"definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTMR",
"dynamicValue" : [
{
"path" : "status",
"expression" : {
"language" : "text/cql-expression",
"expression" : "'draft'"
}
},
{
"path" : "intent",
"expression" : {
"language" : "text/cql-expression",
"expression" : "'proposal'"
}
},
{
"path" : "medication",
"expression" : {
"language" : "text/cql-expression",
"expression" : "Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE21', display: 'Typhoid vaccines' } }, display: 'Typhoid vaccines' }"
}
}
]
},
{
"title" : "Check for Guidance for the patient regarding IMMZ.D2.DT.Typhoid.TCV.",
"description" : "Show Guidance for the patient regarding IMMZ.D2.DT.Typhoid.TCV.",
"condition" : [
{
"kind" : "applicability",
"expression" : {
"description" : "Has Guidance",
"language" : "text/cql-identifier",
"expression" : "Has Guidance"
}
}
],
"definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
"dynamicValue" : [
{
"path" : "status",
"expression" : {
"language" : "text/cql-expression",
"expression" : "'active'"
}
},
{
"path" : "payload.contentString",
"expression" : {
"language" : "text/cql-identifier",
"expression" : "Guidance"
}
},
{
"path" : "category.coding",
"expression" : {
"description" : "Category of communication",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"
}
},
{
"path" : "priority",
"expression" : {
"description" : "Alert priority",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
}
}
]
}
]
}