Id: IMMZD2DTJELiveRecombinantVaccine Url: IMMZ.D2.DT.JE.Live recombinant vaccine Version: 1.0.0 Title: IMMZ.D2.DT.JE.Live recombinant vaccine Status: draft Type: system: http://terminology.hl7.org/CodeSystem/plan-definition-type code: eca-rule Date: 2026-03-31 13:54:17+0000 Publisher: WHO Description: IMMZ.D2.DT.JE.Live recombinant vaccine Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority Knowledge Capability: computable Related Artifacts: References WHO recommendations for routine immunization - summary tables (January 2025) Libraries: IMMZD2DTJELiveRecombinantVaccineLogic Actions: Determine if the client is due for JE.: Determine if the client is due for JE vaccine according to the national immunization protocol. Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority If: Applicability: Client is due for JE vaccination (Client is due for JE vaccination) Then: Definition: IMMZD2DTMR Dynamic Values: status: ('draft') intent: ('proposal') medication: (Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE8', display: 'JE vaccines' } }, display: 'JE vaccines' }) Check for Guidance for the patient regarding IMMZ.D2.DT.JE.Live recombinant vaccine.: Show Guidance for the patient regarding IMMZ.D2.DT.JE.Live recombinant vaccine. If: Applicability: Has Guidance (Has Guidance) Then: Definition: IMMZ.D2.DT.CR Dynamic Values: status: ('active') payload.contentString: (Guidance) category.coding: (Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }) priority: (Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })
/** * @dataElement Patient age in months */ define "Current Patient Age In Months": AgeInMonthsAt(Today)
/* @input: Client's age is less than 9 months @pseudocode: Today's date − "Date of birth" < 9 months @code: Client's age is less than 9 months-41 @decision: IMMZ.D2.DT.JE.Live recombinant vaccine: Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "Client's age is less than 9 months": Encounter."Current Patient Age In Months" < 9
Client is not due for JE vaccination Case 1
/* @output: Client is not due for JE vaccination Case 1 @pseudocode: "Immunization recommendation status" = "Not due" */ define "Client is not due for JE vaccination Case 1": Encounter."Client's age is less than 9 months"
/** * @dataElement All Doses Administered to Patient */ define "Doses Administered to Patient": [Immunization] I where I.status = 'completed' and I.isSubpotent is not true
/** * @dataElement All Doses Administered to Patient */ define "Doses Administered to Patient": Elements."Doses Administered to Patient" I where I.occurrence.toInterval() same day or before Today
/* @internal: JE containing Doses Administered to Patient */ define "JE Doses Administered to Patient": Encounter."Doses Administered to Patient" I where I.vaccineCode in Concepts."JE vaccines"
JE Primary Series Doses Administered to Patient
/* @internal: JE containing Doses Administered to Patient that are in the Primary series */ define "JE Primary Series Doses Administered to Patient": "JE Doses Administered to Patient".seriesPrimary()
Number of JE Primary Series Doses Administered
/* @internal: Number of JE Primary Series doses */ define "Number of JE Primary Series Doses Administered": Count("JE Primary Series Doses Administered to Patient")
No JE primary series doses were administered
/* @input: No JE primary series doses were administered @pseudocode: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 0 @code: No JE primary series doses were administered-111 @decision: IMMZ.D2.DT.JE.Inactivated Vero cell-derived vaccine: Inactivated Vero cell-derived vaccination schedule (2-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live attenuated vaccine: Live attenuated vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live recombinant vaccine: Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "No JE primary series doses were administered": "Number of JE Primary Series Doses Administered" = 0
Client's age is more than or equal to 9 months
/* @input: Client's age is more than or equal to 9 months @pseudocode: Today's date − "Date of birth" ≥ 9 months @code: Client's age is more than or equal to 9 months-41 @decision: IMMZ.D2.DT.JE.Live recombinant vaccine: Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "Client's age is more than or equal to 9 months": Encounter."Current Patient Age In Months" >= 9
/* @dataElement: Live attenuated vaccines */ define "Live Attenuated Vaccines": "Doses Administered to Patient" I where I.vaccineCode in Concepts."Live Attenuated"
/* @dataElement Live attenuated vaccines */ define "Live Attenuated Vaccines": Elements."Live Attenuated Vaccines" I where I.occurrence.toInterval() same day or before Today
/* @dataElement Date and time of last live attenuated vaccine */ define "Date of Latest Live Attenuated Vaccine": date from start of "Live Attenuated Vaccines".mostRecent().occurrence.toInterval()
Live vaccine was administered in the last 4 weeks
/* @input: Live vaccine was administered in the last 4 weeks @pseudocode: Today's date − latest "Date and time of vaccination" (where "Live vaccine" = TRUE) < 4 weeks */ define "Live vaccine was administered in the last 4 weeks": "Date of Latest Live Attenuated Vaccine" is not null and duration in weeks between "Date of Latest Live Attenuated Vaccine" and Today < 4
/* @input: Live vaccine was administered in the last 4 weeks @pseudocode: Today's date − latest "Date and time of vaccination" (where "Live vaccine" = TRUE) < 4 weeks @code: Live vaccine was administered in the last 4 weeks-92 @decision: IMMZ.D2.DT.JE.Live attenuated vaccine: Live attenuated vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live recombinant vaccine: Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "Live vaccine was administered in the last 4 weeks": Encounter."Live vaccine was administered in the last 4 weeks"
Client is not due for JE vaccination Case 2
/* @output: Client is not due for JE vaccination Case 2 @pseudocode: "Immunization recommendation status" = "Not due" */ define "Client is not due for JE vaccination Case 2": Encounter."No JE primary series doses were administered" and Encounter."Client's age is more than or equal to 9 months" and Encounter."Live vaccine was administered in the last 4 weeks"
/* @output: Client is not due for JE vaccination @pseudocode: "Immunization recommendation status" = "Not due" */ define "Client is not due for JE vaccination": "Client is not due for JE vaccination Case 1" or "Client is not due for JE vaccination Case 2"
Client is not due for JE vaccination Guidance
/* @output: Client is not due for JE vaccination Guidance @guidance = Should not vaccinate client with JE dose as client's age is less than 9 months. Check for any vaccines due and inform the caregiver of when to come back for the first JE dose. @guidance = Should not vaccinate client with JE dose as live vaccine was administered in the last 4 weeks. Check for any other vaccines due and inform the caregiver of when to come back for the first JE dose. */ define "Client is not due for JE vaccination Guidance": case when "Client is not due for JE vaccination Case 1" then 'Should not vaccinate client with JE dose as client\'s age is less than 9 months. Check for any vaccines due and inform the caregiver of when to come back for the first JE dose.' when "Client is not due for JE vaccination Case 2" then 'Should not vaccinate client with JE dose as live vaccine was administered in the last 4 weeks. Check for any other vaccines due and inform the caregiver of when to come back for the first JE dose.' else '' end
No live vaccine was administered in the last 4 weeks
/* @input: No live vaccine was administered in the last 4 weeks @pseudocode: Today's date − latest "Date and time of vaccination" (where "Live vaccine" = TRUE) ≥ 4 weeks */ define "No live vaccine was administered in the last 4 weeks": not("Live vaccine was administered in the last 4 weeks")
/* @input: No live vaccine was administered in the last 4 weeks @pseudocode: Today's date − latest "Date and time of vaccination" (where "Vaccine type" = "JE vaccines") ≥ 4 weeks @code: No live vaccine was administered in the last 4 weeks-101 @decision: IMMZ.D2.DT.JE.Live attenuated vaccine: Live attenuated vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live recombinant vaccine: Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "No live vaccine was administered in the last 4 weeks": Encounter."No live vaccine was administered in the last 4 weeks"
/* @output: Client is due for JE vaccination @pseudocode: "Immunization recommendation status" = "Due" */ define "Client is due for JE vaccination": Encounter."No JE primary series doses were administered" and Encounter."Client's age is more than or equal to 9 months" and Encounter."No live vaccine was administered in the last 4 weeks"
Client is due for JE vaccination Guidance
/* @output: Client is due for JE vaccination Guidance @guidance: Should vaccinate client with JE dose as no JE dose was administered, client is within the appropriate age range and no live vaccine was administered in past 4 weeks. Check for contraindications. */ define "Client is due for JE vaccination Guidance": 'Should vaccinate client with JE dose as no JE dose was administered, client is within the appropriate age range and no live vaccine was administered in past 4 weeks. Check for contraindications.'
One JE primary series dose was administered
/* @input: One JE primary series dose was administered @pseudocode: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 1 @code: One JE primary series dose was administered-111 @decision: IMMZ.D2.DT.JE.Inactivated Vero cell-derived vaccine: Inactivated Vero cell-derived vaccination schedule (2-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live attenuated vaccine: Live attenuated vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "One JE primary series dose was administered": "Number of JE Primary Series Doses Administered" = 1
One JE primary series doses were administered
/* @input: One JE primary series doses were administered @pseudocode: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 1 @code: One JE primary series doses were administered-111 @decision: IMMZ.D2.DT.JE.Live recombinant vaccine: Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "One JE primary series doses were administered": "One JE primary series dose was administered"
/* @output: JE immunization schedule is complete @pseudocode: "Immunization recommendation status" = "Complete" "Completed the primary vaccination series" = TRUE (where "Vaccine type" = "JE vaccines") */ define "JE immunization schedule is complete": Encounter."One JE primary series doses were administered"
JE immunization schedule is complete Guidance
/* @output: JE immunization schedule is complete Guidance @guidance: JE immunization schedule is complete. One JE primary series dose was administered. Check for any other vaccines due. */ define "JE immunization schedule is complete Guidance": 'JE immunization schedule is complete. One JE primary series dose was administered. Check for any other vaccines due.'
/* @dynamicValue: Guidance */ define "Guidance": case when "Client is not due for JE vaccination" then "Client is not due for JE vaccination Guidance" when "Client is due for JE vaccination" then "Client is due for JE vaccination Guidance" when "JE immunization schedule is complete" then "JE immunization schedule is complete Guidance" else '' end
define "Has Guidance": "Guidance" is not null and "Guidance" != ''
/** * @description: Gets the doses from the primary series */ define fluent function seriesPrimary(immunizations List<Immunization>): immunizations I where exists( I.protocolApplied pa where pa.series = 'Primary series' )
define function ToString(value string): value.value
define function ToString(value ImmunizationStatus): value.value
define function ToBoolean(value boolean): value.value
/* From FHIRCommon 4.1.0: */ /* @description: Normalizes a value that is a choice of timing-valued types to an equivalent interval @comment: Normalizes a choice type of FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instance, FHIR.string, FHIR.Age, or FHIR.Range types to an equivalent interval. This selection of choice types is a superset of the majority of choice types that are used as possible representations for timing-valued elements in FHIR, allowing this function to be used across any resource. The input can be provided as a dateTime, Period, Timing, instant, string, Age, or Range. The intent of this function is to provide a clear and concise mechanism to treat single elements that have multiple possible representations as intervals so that logic doesn't have to account for the variability. More complex calculations (such as medication request period or dispense period calculation) need specific guidance and consideration. That guidance may make use of this function, but the focus of this function is on single element calculations where the semantics are unambiguous. If the input is a dateTime, the result a DateTime Interval beginning and ending on that dateTime. If the input is a Period, the result is a DateTime Interval. If the input is a Timing, an error is raised indicating a single interval cannot be computed from a Timing. If the input is an instant, the result is a DateTime Interval beginning and ending on that instant. If the input is a string, an error is raised indicating a single interval cannot be computed from a string. If the input is an Age, the result is a DateTime Interval beginning when the patient was the given Age, and ending immediately prior to when the patient was the given Age plus one year. If the input is a Range, the result is a DateTime Interval beginning when the patient was the Age given by the low end of the Range, and ending immediately prior to when the patient was the Age given by the high end of the Range plus one year. NOTE: Due to the complexity of determining a single interval from a Timing or String type, this function will throw a run-time exception if it is used with a Timing or String. */ define fluent function toInterval(choice Choice<FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instant, FHIR.string, FHIR.Age, FHIR.Range>): case when choice is FHIR.dateTime then Interval[FHIRHelpers.ToDateTime(choice as FHIR.dateTime), FHIRHelpers.ToDateTime(choice as FHIR.dateTime)] when choice is FHIR.Period then FHIRHelpers.ToInterval(choice as FHIR.Period) when choice is FHIR.instant then Interval[FHIRHelpers.ToDateTime(choice as FHIR.instant), FHIRHelpers.ToDateTime(choice as FHIR.instant)] when choice is FHIR.Age then Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age), FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age) + 1 year) when choice is FHIR.Range then Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).low), FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).high) + 1 year) when choice is FHIR.Timing then Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a Timing value is not supported') when choice is FHIR.string then Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a String value is not supported') else null as Interval<DateTime> end
define function ToDateTime(value dateTime): value.value
define function ToInterval(period FHIR.Period): if period is null then null else if period."start" is null then Interval(period."start".value, period."end".value] else Interval[period."start".value, period."end".value]
define function ToDateTime(value instant): value.value
define function ToDate(value date): value.value
define function ToQuantity(quantity FHIR.Quantity): case when quantity is null then null when quantity.value is null then null when quantity.comparator is not null then Message(null, true, 'FHIRHelpers.ToQuantity.ComparatorQuantityNotSupported', 'Error', 'FHIR Quantity value has a comparator and cannot be converted to a System.Quantity value.') when quantity.system is null or quantity.system.value = 'http://unitsofmeasure.org' or quantity.system.value = 'http://hl7.org/fhirpath/CodeSystem/calendar-units' then System.Quantity { value: quantity.value.value, unit: ToCalendarUnit(Coalesce(quantity.code.value, quantity.unit.value, '1')) } else Message(null, true, 'FHIRHelpers.ToQuantity.InvalidFHIRQuantity', 'Error', 'Invalid FHIR Quantity code: ' & quantity.unit.value & ' (' & quantity.system.value & '|' & quantity.code.value & ')') end
define function ToCalendarUnit(unit System.String): case unit when 'ms' then 'millisecond' when 's' then 'second' when 'min' then 'minute' when 'h' then 'hour' when 'd' then 'day' when 'wk' then 'week' when 'mo' then 'month' when 'a' then 'year' else unit end
define function ToConcept(concept FHIR.CodeableConcept): if concept is null then null else System.Concept { codes: concept.coding C return ToCode(C), display: concept.text.value }
define function ToCode(coding FHIR.Coding): if coding is null then null else System.Code { code: coding.code.value, system: coding.system.value, version: coding.version.value, display: coding.display.value }
define fluent function mostRecent(immunizations List<Immunization>): Last( immunizations I sort by start of occurrence.toInterval() )
IMMZ.D2.DT.JE.Live recombinant vaccine Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority
WHO recommendations for routine immunization - summary tables (January 2025)
Live recombinant vaccine: Single dose administered at ≥ 9 months of age. As a general rule, any live vaccine may be given either simultaneously or at an interval of 4 weeks.
Determine if the client is due for JE vaccine according to the national immunization protocol. Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority
Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE8', display: 'JE vaccines' } }, display: 'JE vaccines' }
Check for Guidance for the patient regarding IMMZ.D2.DT.JE.Live recombinant vaccine.
Show Guidance for the patient regarding IMMZ.D2.DT.JE.Live recombinant vaccine.
Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }
Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }