Id: IMMZD18SJEInactivatedVeroCellDerivedVaccine Url: IMMZ.D18.S.JE.Inactivated Vero cell-derived vaccination schedule Version: 1.0.0 Title: IMMZ.D18.S.JE.Inactivated Vero cell-derived vaccination schedule Status: draft Type: system: http://terminology.hl7.org/CodeSystem/plan-definition-type code: eca-rule Date: 2026-03-31 13:54:17+0000 Publisher: WHO Description: IMMZ.D18.S.JE.Inactivated Vero cell-derived vaccination schedule Inactivated Vero cell-derived vaccination schedule (2-dose scheme) Knowledge Capability: computable Related Artifacts: References WHO recommendations for routine immunization - summary tables (January 2025) Libraries: IMMZD18SJEInactivatedVeroCellDerivedVaccineLogic Actions: Japanese encephalitis (JE) dose 1: Provision of the JE dose 1 Trigger event: Child's birth Trigger pseudo: Trigger date: "Date of birth" Create condition: JE dose 1 should be provided if the client's age is 6 months or older and the country is administering the Inactivated Vero cell-derived antigen. If: Applicability: Japanese encephalitis (JE) dose 1 (Japanese encephalitis (JE) dose 1) Then: Definition: IMMZ.D2.DT.CR Dynamic Values: status: ('active') payload.contentString: (Japanese encephalitis (JE) dose 1 Create) category.coding: (Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }) priority: (Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }) JE dose 2: Provision of the JE dose 2 Trigger event: One JE primary series dose was administered Trigger pseudo: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 1 Trigger date: "Date and time of vaccination" where "Vaccine type" = "JE vaccines" Create condition: JE inactivated Vero cell-derived vaccine dose 2 should be provided if dose 1 was administered at least 4 weeks ago. If: Applicability: JE dose 2 (JE dose 2) Then: Definition: IMMZ.D2.DT.CR Dynamic Values: status: ('active') payload.contentString: (JE dose 2 Create) category.coding: (Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }) priority: (Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })
/** * @dataElement All Doses Administered to Patient */ define "Doses Administered to Patient": [Immunization] I where I.status = 'completed' and I.isSubpotent is not true
/** * @dataElement All Doses Administered to Patient */ define "Doses Administered to Patient": Elements."Doses Administered to Patient" I where I.occurrence.toInterval() same day or before Today
/* @internal: JE containing Doses Administered to Patient */ define "JE Doses Administered to Patient": Encounter."Doses Administered to Patient" I where I.vaccineCode in Concepts."JE vaccines"
JE Primary Series Doses Administered to Patient
/* @internal: JE containing Doses Administered to Patient that are in the Primary series */ define "JE Primary Series Doses Administered to Patient": "JE Doses Administered to Patient".seriesPrimary()
Number of JE Primary Series Doses Administered
/* @internal: Number of JE Primary Series doses */ define "Number of JE Primary Series Doses Administered": Count("JE Primary Series Doses Administered to Patient")
No JE primary series doses were administered
/* @input: No JE primary series doses were administered @pseudocode: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 0 @code: No JE primary series doses were administered-111 @decision: IMMZ.D2.DT.JE.Inactivated Vero cell-derived vaccine: Inactivated Vero cell-derived vaccination schedule (2-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live attenuated vaccine: Live attenuated vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live recombinant vaccine: Live recombinant vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "No JE primary series doses were administered": "Number of JE Primary Series Doses Administered" = 0
/* @output: Japanese encephalitis (JE) dose 1 @description: Provision of the JE dose 1 @trigger: Child's birth @pseudo: @triggerDate: "Date of birth" */ define "Japanese encephalitis (JE) dose 1": Encounter."No JE primary series doses were administered"
One JE primary series dose was administered
/* @input: One JE primary series dose was administered @pseudocode: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 1 @code: One JE primary series dose was administered-111 @decision: IMMZ.D2.DT.JE.Inactivated Vero cell-derived vaccine: Inactivated Vero cell-derived vaccination schedule (2-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority @decision: IMMZ.D2.DT.JE.Live attenuated vaccine: Live attenuated vaccination schedule (1-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "One JE primary series dose was administered": "Number of JE Primary Series Doses Administered" = 1
/* @complete: One JE primary series dose was administered @pseudocode: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 1 */ define "One JE primary series dose was administered": Encounter."One JE primary series dose was administered"
Two JE primary series doses were administered
/* @input: Two JE primary series doses were administered @pseudocode: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 2 @code: Two JE primary series doses were administered-111 @decision: IMMZ.D2.DT.JE.Inactivated Vero cell-derived vaccine: Inactivated Vero cell-derived vaccination schedule (2-dose scheme) JE vaccination should be integrated into national immunization schedules in all areas where JE is recognized as a public health priority */ define "Two JE primary series doses were administered": "Number of JE Primary Series Doses Administered" = 2
Second JE dose from the primary series was administered. The primary series has been completed
/* @complete: Second JE dose from the primary series was administered. The primary series has been completed @pseudocode: "Completed the primary vaccination series" = TRUE (where "Vaccine type" = "JE vaccines") */ define "Second JE dose from the primary series was administered. The primary series has been completed": Encounter."Two JE primary series doses were administered"
/* @output: JE dose 2 @description: Provision of the JE dose 2 @trigger: One JE primary series dose was administered @pseudo: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 1 @triggerDate: "Date and time of vaccination" where "Vaccine type" = "JE vaccines" */ define "JE dose 2": "One JE primary series dose was administered" and not "Second JE dose from the primary series was administered. The primary series has been completed"
/* @internal: Date of Latest JE Dose */ define "Date of Latest JE Dose": date from start of "JE Doses Administered to Patient".mostRecent().occurrence.toInterval()
/* @dynamicValue: JE dose 2 Due Date @pseudocode: "Date and time of vaccination" (where "Vaccine type" = "JE vaccines") + 4 weeks */ define "JE dose 2 Due Date": if "JE dose 2" then Encounter."Date of Latest JE Dose" + 4 weeks else null
/* @output: JE dose 2 Create @create: JE inactivated Vero cell-derived vaccine dose 2 should be provided if dose 1 was administered at least 4 weeks ago. */ define "JE dose 2 Create": if "JE dose 2" then 'JE inactivated Vero cell-derived vaccine dose 2 should be provided if dose 1 was administered at least 4 weeks ago.' + ' Due Date: ' + ToString("JE dose 2 Due Date") else ''
Japanese encephalitis (JE) dose 1 Due Date
/* @dynamicValue: Japanese encephalitis (JE) dose 1 Due Date @pseudocode: "Date of birth"+ 6 months */ define "Japanese encephalitis (JE) dose 1 Due Date": if "Japanese encephalitis (JE) dose 1" then Patient.birthDate + 6 months else null
Japanese encephalitis (JE) dose 1 Create
/* @output: Japanese encephalitis (JE) dose 1 Create @create: JE dose 1 should be provided if the client's age is 6 months or older and the country is administering the Inactivated Vero cell-derived antigen. */ define "Japanese encephalitis (JE) dose 1 Create": if "Japanese encephalitis (JE) dose 1" then 'JE dose 1 should be provided if the client\'s age is 6 months or older and the country is administering the Inactivated Vero cell-derived antigen.' + ' Due Date: ' + ToString("Japanese encephalitis (JE) dose 1 Due Date") else ''
/** * @description: Gets the doses from the primary series */ define fluent function seriesPrimary(immunizations List<Immunization>): immunizations I where exists( I.protocolApplied pa where pa.series = 'Primary series' )
define function ToString(value string): value.value
define function ToString(value ImmunizationStatus): value.value
define function ToBoolean(value boolean): value.value
/* From FHIRCommon 4.1.0: */ /* @description: Normalizes a value that is a choice of timing-valued types to an equivalent interval @comment: Normalizes a choice type of FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instance, FHIR.string, FHIR.Age, or FHIR.Range types to an equivalent interval. This selection of choice types is a superset of the majority of choice types that are used as possible representations for timing-valued elements in FHIR, allowing this function to be used across any resource. The input can be provided as a dateTime, Period, Timing, instant, string, Age, or Range. The intent of this function is to provide a clear and concise mechanism to treat single elements that have multiple possible representations as intervals so that logic doesn't have to account for the variability. More complex calculations (such as medication request period or dispense period calculation) need specific guidance and consideration. That guidance may make use of this function, but the focus of this function is on single element calculations where the semantics are unambiguous. If the input is a dateTime, the result a DateTime Interval beginning and ending on that dateTime. If the input is a Period, the result is a DateTime Interval. If the input is a Timing, an error is raised indicating a single interval cannot be computed from a Timing. If the input is an instant, the result is a DateTime Interval beginning and ending on that instant. If the input is a string, an error is raised indicating a single interval cannot be computed from a string. If the input is an Age, the result is a DateTime Interval beginning when the patient was the given Age, and ending immediately prior to when the patient was the given Age plus one year. If the input is a Range, the result is a DateTime Interval beginning when the patient was the Age given by the low end of the Range, and ending immediately prior to when the patient was the Age given by the high end of the Range plus one year. NOTE: Due to the complexity of determining a single interval from a Timing or String type, this function will throw a run-time exception if it is used with a Timing or String. */ define fluent function toInterval(choice Choice<FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instant, FHIR.string, FHIR.Age, FHIR.Range>): case when choice is FHIR.dateTime then Interval[FHIRHelpers.ToDateTime(choice as FHIR.dateTime), FHIRHelpers.ToDateTime(choice as FHIR.dateTime)] when choice is FHIR.Period then FHIRHelpers.ToInterval(choice as FHIR.Period) when choice is FHIR.instant then Interval[FHIRHelpers.ToDateTime(choice as FHIR.instant), FHIRHelpers.ToDateTime(choice as FHIR.instant)] when choice is FHIR.Age then Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age), FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age) + 1 year) when choice is FHIR.Range then Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).low), FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).high) + 1 year) when choice is FHIR.Timing then Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a Timing value is not supported') when choice is FHIR.string then Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a String value is not supported') else null as Interval<DateTime> end
define function ToDateTime(value dateTime): value.value
define function ToInterval(period FHIR.Period): if period is null then null else if period."start" is null then Interval(period."start".value, period."end".value] else Interval[period."start".value, period."end".value]
define function ToDateTime(value instant): value.value
define function ToDate(value date): value.value
define function ToQuantity(quantity FHIR.Quantity): case when quantity is null then null when quantity.value is null then null when quantity.comparator is not null then Message(null, true, 'FHIRHelpers.ToQuantity.ComparatorQuantityNotSupported', 'Error', 'FHIR Quantity value has a comparator and cannot be converted to a System.Quantity value.') when quantity.system is null or quantity.system.value = 'http://unitsofmeasure.org' or quantity.system.value = 'http://hl7.org/fhirpath/CodeSystem/calendar-units' then System.Quantity { value: quantity.value.value, unit: ToCalendarUnit(Coalesce(quantity.code.value, quantity.unit.value, '1')) } else Message(null, true, 'FHIRHelpers.ToQuantity.InvalidFHIRQuantity', 'Error', 'Invalid FHIR Quantity code: ' & quantity.unit.value & ' (' & quantity.system.value & '|' & quantity.code.value & ')') end
define function ToCalendarUnit(unit System.String): case unit when 'ms' then 'millisecond' when 's' then 'second' when 'min' then 'minute' when 'h' then 'hour' when 'd' then 'day' when 'wk' then 'week' when 'mo' then 'month' when 'a' then 'year' else unit end
define function ToConcept(concept FHIR.CodeableConcept): if concept is null then null else System.Concept { codes: concept.coding C return ToCode(C), display: concept.text.value }
define function ToCode(coding FHIR.Coding): if coding is null then null else System.Code { code: coding.code.value, system: coding.system.value, version: coding.version.value, display: coding.display.value }
define fluent function mostRecent(immunizations List<Immunization>): Last( immunizations I sort by start of occurrence.toInterval() )
IMMZ.D18.S.JE.Inactivated Vero cell-derived vaccination schedule
IMMZ.D18.S.JE.Inactivated Vero cell-derived vaccination schedule Inactivated Vero cell-derived vaccination schedule (2-dose scheme)
WHO recommendations for routine immunization - summary tables (January 2025)
Provision of the JE dose 1 Trigger event: Child's birth Trigger pseudo: Trigger date: "Date of birth" Create condition: JE dose 1 should be provided if the client's age is 6 months or older and the country is administering the Inactivated Vero cell-derived antigen.
Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }
Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }
Provision of the JE dose 2 Trigger event: One JE primary series dose was administered Trigger pseudo: Count of vaccines administered (where "Vaccine type" = "JE vaccines" and "Type of dose" = "Primary series") = 1 Trigger date: "Date and time of vaccination" where "Vaccine type" = "JE vaccines" Create condition: JE inactivated Vero cell-derived vaccine dose 2 should be provided if dose 1 was administered at least 4 weeks ago.