WHO Immunization Implementation Guide
1.0.0 - release
WHO Immunization Implementation Guide
1.0.0 - release
WHO Immunization Implementation Guide, published by WHO. This guide is not an authorized publication; it is the continuous build for version 1.0.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/WorldHealthOrganization/smart-immunizations/tree/132/merge and changes regularly. See the Directory of published versions
| Draft as of 2026-03-31 |
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"div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n<div>\n <table class=\"grid dict\">\n \n <tr>\n <th scope=\"row\"><b>Id: </b></th>\n <td style=\"padding-left: 4px;\">IMMZD18SCholeraWCVaccines</td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Url: </b></th>\n <td style=\"padding-left: 4px;\"><a href=\"PlanDefinition-IMMZD18SCholeraWCVaccines.html\">IMMZ.D18.S.Cholera.WC vaccines schedule</a></td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Version: </b></th>\n <td style=\"padding-left: 4px;\">1.0.0</td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Title: </b></th>\n <td style=\"padding-left: 4px;\">IMMZ.D18.S.Cholera.WC vaccines schedule</td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Status: </b></th>\n <td style=\"padding-left: 4px;\">draft</td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Type: </b></th>\n <td style=\"padding-left: 4px;\">\n \n \n \n <p style=\"margin-bottom: 5px;\">\n <b>system: </b> <span><a href=\"http://terminology.hl7.org/7.1.0/CodeSystem-plan-definition-type.html\">http://terminology.hl7.org/CodeSystem/plan-definition-type</a></span>\n </p>\n \n \n <p style=\"margin-bottom: 5px;\">\n <b>code: </b> <span>eca-rule</span>\n </p>\n \n \n \n \n \n </td>\n </tr>\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Date: </b></th>\n <td style=\"padding-left: 4px;\">2026-03-31 13:54:17+0000</td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Publisher: </b></th>\n <td style=\"padding-left: 4px;\">WHO</td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Description: </b></th>\n <td style=\"padding-left: 4px;\"><div><p>IMMZ.D18.S.Cholera.WC vaccines schedule\nWhole-cell (WC) vaccines (Shanchol, Euvchol and mORCVAX), 2-dose schedule</p>\n</div></td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Knowledge Capability: </b></th>\n <td style=\"padding-left: 4px;\">\n \n computable \n </td>\n </tr>\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n\n \n <tr>\n <th scope=\"row\"><b>Related Artifacts: </b></th>\n <td style=\"padding-left: 4px;\">\n \n \n <p><b>References</b></p>\n <ul>\n \n <li><div><p>WHO recommendations for routine immunization - summary tables (January 2025)</p>\n</div><br/><a href=\"null\"/></li>\n \n </ul>\n \n \n \n \n \n \n </td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Libraries: </b></th>\n <td style=\"padding-left: 4px;\">\n <table class=\"grid-dict\">\n \n <tr>\n <td><a href=\"Library-IMMZD18SCholeraWCVaccinesLogic.html\">IMMZD18SCholeraWCVaccinesLogic</a></td>\n </tr>\n \n </table>\n </td>\n </tr>\n \n\n \n <tr>\n <th scope=\"row\"><b>Actions: </b></th>\n <td style=\"padding-left: 4px;\">\n <table class=\"grid-dict\">\n \n <tr>\n <td>\n \n <b> Cholera dose 1:</b> Provision of the cholera dose 1\nTrigger event: Child's birth and no cholera doses have been administered\nTrigger pseudo: Child's birth AND Count of vaccines administered (where "Vaccine type" = "Cholera vaccines" and "Type of dose" = "Primary series") = 0\nTrigger date: "Date of birth"\nOR\nLatest "Date and time of vaccination" (where "Vaccine type" = "Cholera vaccines")\nCreate condition: WC vaccines: 2 doses should be given 14 days apart to individuals aged ≥ 1 year.\nRevaccination is recommended where there is continued risk of Vibrio cholerae infection. For WC vaccines, revaccination is recommended after 3 years.\n \n <br/>\n \n \n <b>If:</b>\n \n <i>Applicability:</i>\n \n Cholera dose 1\n \n <i>(Cholera dose 1)</i>\n <br/>\n \n \n \n \n <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n \n <i>Dynamic Values:</i><br/>\n \n status: <i>('active')</i>\n <br/>\n \n payload.contentString: <i>(Cholera dose 1 Create)</i>\n <br/>\n \n category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n <br/>\n \n priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n <br/>\n \n \n \n \n </td>\n </tr>\n \n <tr>\n <td>\n \n <b> Cholera dose 2:</b> Provision of the cholera dose 2\nTrigger event: First cholera dose administered\nTrigger pseudo: Latest "Dose number" (where "Vaccine type" = "Cholera vaccines"and "Type of dose" = "Primary series") = 1\nTrigger date: Latest "Date and time of vaccination" (where "Vaccine type" = "Cholera vaccines")\nCreate condition: WC vaccines: 2 doses should be given 14 days apart to individuals aged ≥ 1 year.\n \n <br/>\n \n \n <b>If:</b>\n \n <i>Applicability:</i>\n \n Cholera dose 2\n \n <i>(Cholera dose 2)</i>\n <br/>\n \n \n \n \n <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n \n <i>Dynamic Values:</i><br/>\n \n status: <i>('active')</i>\n <br/>\n \n payload.contentString: <i>(Cholera dose 2 Create)</i>\n <br/>\n \n category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n <br/>\n \n priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n <br/>\n \n \n \n \n </td>\n </tr>\n \n <tr>\n <td>\n \n <b> Cholera booster dose 1:</b> Provision of the cholera booster dose 1\nTrigger event: Primary series for cholera has been completed and latest cholera dose was administered more than 3 years ago\nTrigger pseudo: "Completed the primary vaccination series" (where "Vaccine type" = "Cholera vaccines") = TRUE AND Today's date − latest "Date and time of vaccination" (where "Vaccine type" = "Cholera vaccines") ≥ 3 years\nTrigger date: Latest "Date and time of vaccination" (where "Vaccine type" = "Cholera vaccines")\nCreate condition: For WC vaccines, revaccination is recommended after 3 years.\n \n <br/>\n \n \n <b>If:</b>\n \n <i>Applicability:</i>\n \n Cholera booster dose 1\n \n <i>(Cholera booster dose 1)</i>\n <br/>\n \n \n \n \n <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n \n <i>Dynamic Values:</i><br/>\n \n status: <i>('active')</i>\n <br/>\n \n payload.contentString: <i>(Cholera booster dose 1 Create)</i>\n <br/>\n \n category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n <br/>\n \n priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n <br/>\n \n \n \n \n </td>\n </tr>\n \n <tr>\n <td>\n \n <b> Cholera booster dose 2:</b> Provision of the cholera booster dose 1\nTrigger event: First cholera booster dose administered\nTrigger pseudo: Latest "Dose number" (where "Vaccine type" = "Cholera vaccines"and "Type of dose" = "Booster dose") = 1\nTrigger date: Latest "Date and time of vaccination" (where "Vaccine type" = "Cholera vaccines")\nCreate condition: For WC vaccines, revaccination is recommended after 3 years.\n \n <br/>\n \n \n <b>If:</b>\n \n <i>Applicability:</i>\n \n Cholera booster dose 2\n \n <i>(Cholera booster dose 2)</i>\n <br/>\n \n \n \n \n <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n \n <i>Dynamic Values:</i><br/>\n \n status: <i>('active')</i>\n <br/>\n \n payload.contentString: <i>(Cholera booster dose 2 Create)</i>\n <br/>\n \n category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n <br/>\n \n priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n <br/>\n \n \n \n \n </td>\n </tr>\n \n </table>\n </td>\n </tr>\n \n </table>\n</div>\n</div>"
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"url" : "statement",
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"url" : "statement",
"valueString" : "/*\n@input: At least one booster series dose was administered\n@pseudocode: Count of vaccines administered (where \"Vaccine type\" = \"Cholera vaccines\" and \"Type of dose\" = \"Booster dose\") >= 1\n@code: At least one booster series dose was administered-115\n@decision: IMMZ.D2.DT.Cholera.WC vaccines: Whole-cell (WC) vaccines schedule\n*/\ndefine \"At least one booster series dose was administered\":\n \"Number of Cholera Booster Series Doses Administered\" >= 1"
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"valueString" : "/*\n@output: Cholera booster dose 1\n@description: Provision of the cholera booster dose 1\n@trigger: Primary series for cholera has been completed and latest cholera dose was administered more than 3 years ago\n@pseudo: \"Completed the primary vaccination series\" (where \"Vaccine type\" = \"Cholera vaccines\") = TRUE AND Today's date − latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\") ≥ 3 years\n@triggerDate: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\")\n*/\ndefine \"Cholera booster dose 1\":\n \"The primary series has been completed\"\n and not \"First cholera booster dose was administered\""
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{
"url" : "statement",
"valueString" : "/*\n@dynamicValue: Cholera booster dose 1 Due Date\n@pseudocode: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\") + 2 weeks\n*/\ndefine \"Cholera booster dose 1 Due Date\":\n if \"Cholera booster dose 1\" then Encounter.\"Date of Latest Cholera Dose\" + 3 years\n else null"
},
{
"url" : "displaySequence",
"valueInteger" : 19
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Cholera booster dose 1 Create"
},
{
"url" : "statement",
"valueString" : "/*\n@output: Cholera booster dose 1 Create\n@create: For WC vaccines, revaccination is recommended after 3 years.\n*/\ndefine \"Cholera booster dose 1 Create\":\n if \"Cholera booster dose 1\"\n then 'For WC vaccines, revaccination is recommended after 3 years.' + '\nDue Date: ' + ToString(\"Cholera booster dose 1 Due Date\")\n else ''"
},
{
"url" : "displaySequence",
"valueInteger" : 20
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD2DTCholeraEncounterElements"
},
{
"url" : "name",
"valueString" : "Dose number of the latest dose is two"
},
{
"url" : "statement",
"valueString" : "/*\n@input: Dose number of the latest dose is two\n@pseudocode: Latest \"Dose number\" (where \"Vaccine type\" = \"Cholera vaccines\") = 2\n@code: Dose number of the latest dose is two-68\n@decision: IMMZ.D2.DT.Cholera.WC vaccines: Whole-cell (WC) vaccines schedule\n*/\ndefine \"Dose number of the latest dose is two\":\n \"Cholera Doses Administered to Patient\".mostRecent().getDose('2') is not null"
},
{
"url" : "displaySequence",
"valueInteger" : 21
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Revaccination with booster series has been completed in the last 3 years"
},
{
"url" : "statement",
"valueString" : "/*\n@complete: Revaccination with booster series has been completed in the last 3 years\n@pseudocode: \"Completed the booster series\" (where \"Vaccine type\" = \"Cholera vaccines\") = TRUE AND Today's date − latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccine\") < 3 years\n*/\ndefine \"Revaccination with booster series has been completed in the last 3 years\":\n Encounter.\"At least one booster series dose was administered\"\n and Encounter.\"Dose number of the latest dose is two\""
},
{
"url" : "displaySequence",
"valueInteger" : 22
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Cholera booster dose 2"
},
{
"url" : "statement",
"valueString" : "/*\n@output: Cholera booster dose 2\n@description: Provision of the cholera booster dose 1\n@trigger: First cholera booster dose administered\n@pseudo: Latest \"Dose number\" (where \"Vaccine type\" = \"Cholera vaccines\"and \"Type of dose\" = \"Booster dose\") = 1\n@triggerDate: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\")\n*/\ndefine \"Cholera booster dose 2\":\n \"First cholera booster dose was administered\"\n and not \"Revaccination with booster series has been completed in the last 3 years\""
},
{
"url" : "displaySequence",
"valueInteger" : 23
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD2DTCholeraEncounterElements"
},
{
"url" : "name",
"valueString" : "No cholera primary series dose was administered"
},
{
"url" : "statement",
"valueString" : "/*\n@input: No cholera primary series dose was administered\n@pseudocode: Count of vaccines administered (where \"Vaccine type\" = \"Cholera vaccines\" and \"Type of dose\" = \"Primary series\") = 0\n@code: No cholera primary series dose was administered-116\n@decision: IMMZ.D2.DT.Cholera.WC vaccines: Whole-cell (WC) vaccines schedule\n@decision: IMMZ.D2.DT.Cholera.WC-rBS vaccine 3 doses: Whole cell-recombinant B subunit (WC-rBS) vaccine, 3-dose schedule for clients aged 2–5 years\n@decision: IMMZ.D2.DT.Cholera.WC-rBS vaccine 2 doses: Whole cell-recombinant B subunit (WC-rBS) vaccine, 2-dose schedule for clients aged over 5 years\n*/\ndefine \"No cholera primary series dose was administered\":\n \"Number of Cholera Primary Series Doses Administered\" = 0"
},
{
"url" : "displaySequence",
"valueInteger" : 24
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Cholera dose 1"
},
{
"url" : "statement",
"valueString" : "/*\n@output: Cholera dose 1\n@description: Provision of the cholera dose 1\n@trigger: Child's birth and no cholera doses have been administered\n@pseudo: Child's birth AND Count of vaccines administered (where \"Vaccine type\" = \"Cholera vaccines\" and \"Type of dose\" = \"Primary series\") = 0\n@triggerDate: \"Date of birth\"\nOR\nLatest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\")\n*/\ndefine \"Cholera dose 1\":\n Encounter.\"No cholera primary series dose was administered\"\n and not \"First cholera dose was administered\""
},
{
"url" : "displaySequence",
"valueInteger" : 25
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Cholera booster dose 2 Due Date"
},
{
"url" : "statement",
"valueString" : "/*\n@dynamicValue: Cholera booster dose 2 Due Date\n@pseudocode: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\") + 3 years\n*/\ndefine \"Cholera booster dose 2 Due Date\":\n if \"Cholera booster dose 2\" then Encounter.\"Date of Latest Cholera Dose\" + 2 weeks\n else null"
},
{
"url" : "displaySequence",
"valueInteger" : 26
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Cholera booster dose 2 Create"
},
{
"url" : "statement",
"valueString" : "/*\n@output: Cholera booster dose 2 Create\n@create: For WC vaccines, revaccination is recommended after 3 years.\n*/\ndefine \"Cholera booster dose 2 Create\":\n if \"Cholera booster dose 2\"\n then 'For WC vaccines, revaccination is recommended after 3 years.' + '\nDue Date: ' + ToString(\"Cholera booster dose 2 Due Date\")\n else ''"
},
{
"url" : "displaySequence",
"valueInteger" : 27
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Cholera dose 1 Due Date"
},
{
"url" : "statement",
"valueString" : "/*\n@dynamicValue: Cholera dose 1 Due Date\n@pseudocode: \"Date of birth\" + 1 year\n*/\ndefine \"Cholera dose 1 Due Date\":\n if \"Cholera dose 1\" then Patient.birthDate + 1 year\n else null"
},
{
"url" : "displaySequence",
"valueInteger" : 28
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZD18SCholeraWCVaccinesLogic"
},
{
"url" : "name",
"valueString" : "Cholera dose 1 Create"
},
{
"url" : "statement",
"valueString" : "/*\n@output: Cholera dose 1 Create\n@create: WC vaccines: 2 doses should be given 14 days apart to individuals aged ≥ 1 year.\nRevaccination is recommended where there is continued risk of Vibrio cholerae infection. For WC vaccines, revaccination is recommended after 3 years.\n*/\ndefine \"Cholera dose 1 Create\":\n if \"Cholera dose 1\"\n then 'WC vaccines: 2 doses should be given 14 days apart to individuals aged ≥ 1 year.\nRevaccination is recommended where there is continued risk of Vibrio cholerae infection. For WC vaccines, revaccination is recommended after 3 years.' + '\nDue Date: ' + ToString(\"Cholera dose 1 Due Date\")\n else ''"
},
{
"url" : "displaySequence",
"valueInteger" : 29
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZCommon"
},
{
"url" : "name",
"valueString" : "seriesPrimary"
},
{
"url" : "statement",
"valueString" : "/**\n * @description: Gets the doses from the primary series\n */\ndefine fluent function seriesPrimary(immunizations List<Immunization>):\n immunizations I where\n exists( I.protocolApplied pa where pa.series = 'Primary series' )"
},
{
"url" : "displaySequence",
"valueInteger" : 30
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToString"
},
{
"url" : "statement",
"valueString" : "define function ToString(value string): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 31
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToString"
},
{
"url" : "statement",
"valueString" : "define function ToString(value ImmunizationStatus): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 32
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToBoolean"
},
{
"url" : "statement",
"valueString" : "define function ToBoolean(value boolean): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 33
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "WHOCommon"
},
{
"url" : "name",
"valueString" : "toInterval"
},
{
"url" : "statement",
"valueString" : "/*\nFrom FHIRCommon 4.1.0:\n*/\n\n/*\n@description: Normalizes a value that is a choice of timing-valued types to an equivalent interval\n@comment: Normalizes a choice type of FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instance, FHIR.string, FHIR.Age, or FHIR.Range types\nto an equivalent interval. This selection of choice types is a superset of the majority of choice types that are used as possible\nrepresentations for timing-valued elements in FHIR, allowing this function to be used across any resource.\n\nThe input can be provided as a dateTime, Period, Timing, instant, string, Age, or Range.\nThe intent of this function is to provide a clear and concise mechanism to treat single\nelements that have multiple possible representations as intervals so that logic doesn't have to account\nfor the variability. More complex calculations (such as medication request period or dispense period\ncalculation) need specific guidance and consideration. That guidance may make use of this function, but\nthe focus of this function is on single element calculations where the semantics are unambiguous.\nIf the input is a dateTime, the result a DateTime Interval beginning and ending on that dateTime.\nIf the input is a Period, the result is a DateTime Interval.\nIf the input is a Timing, an error is raised indicating a single interval cannot be computed from a Timing.\nIf the input is an instant, the result is a DateTime Interval beginning and ending on that instant.\nIf the input is a string, an error is raised indicating a single interval cannot be computed from a string.\nIf the input is an Age, the result is a DateTime Interval beginning when the patient was the given Age,\nand ending immediately prior to when the patient was the given Age plus one year.\nIf the input is a Range, the result is a DateTime Interval beginning when the patient was the Age given\nby the low end of the Range, and ending immediately prior to when the patient was the Age given by the\nhigh end of the Range plus one year.\n\nNOTE: Due to the\ncomplexity of determining a single interval from a Timing or String type, this function will throw a run-time exception if it is used\nwith a Timing or String.\n*/\ndefine fluent function toInterval(choice Choice<FHIR.dateTime, FHIR.Period, FHIR.Timing, FHIR.instant, FHIR.string, FHIR.Age, FHIR.Range>):\n case\n when choice is FHIR.dateTime then\n Interval[FHIRHelpers.ToDateTime(choice as FHIR.dateTime), FHIRHelpers.ToDateTime(choice as FHIR.dateTime)]\n when choice is FHIR.Period then\n FHIRHelpers.ToInterval(choice as FHIR.Period)\n when choice is FHIR.instant then\n Interval[FHIRHelpers.ToDateTime(choice as FHIR.instant), FHIRHelpers.ToDateTime(choice as FHIR.instant)]\n when choice is FHIR.Age then\n Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age),\n FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity(choice as FHIR.Age) + 1 year)\n when choice is FHIR.Range then\n Interval[FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).low),\n FHIRHelpers.ToDate(Patient.birthDate) + FHIRHelpers.ToQuantity((choice as FHIR.Range).high) + 1 year)\n when choice is FHIR.Timing then\n Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a Timing value is not supported')\n when choice is FHIR.string then\n Message(null as Interval<DateTime>, true, 'NOT_IMPLEMENTED', 'Error', 'Calculation of an interval from a String value is not supported')\n else\n null as Interval<DateTime>\n end"
},
{
"url" : "displaySequence",
"valueInteger" : 34
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToDateTime"
},
{
"url" : "statement",
"valueString" : "define function ToDateTime(value dateTime): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 35
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToInterval"
},
{
"url" : "statement",
"valueString" : "define function ToInterval(period FHIR.Period):\n if period is null then\n null\n else\n if period.\"start\" is null then\n Interval(period.\"start\".value, period.\"end\".value]\n else\n Interval[period.\"start\".value, period.\"end\".value]"
},
{
"url" : "displaySequence",
"valueInteger" : 36
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToDateTime"
},
{
"url" : "statement",
"valueString" : "define function ToDateTime(value instant): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 37
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToDate"
},
{
"url" : "statement",
"valueString" : "define function ToDate(value date): value.value"
},
{
"url" : "displaySequence",
"valueInteger" : 38
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToQuantity"
},
{
"url" : "statement",
"valueString" : "define function ToQuantity(quantity FHIR.Quantity):\n case\n when quantity is null then null\n when quantity.value is null then null\n when quantity.comparator is not null then\n Message(null, true, 'FHIRHelpers.ToQuantity.ComparatorQuantityNotSupported', 'Error', 'FHIR Quantity value has a comparator and cannot be converted to a System.Quantity value.')\n when quantity.system is null or quantity.system.value = 'http://unitsofmeasure.org'\n or quantity.system.value = 'http://hl7.org/fhirpath/CodeSystem/calendar-units' then\n System.Quantity { value: quantity.value.value, unit: ToCalendarUnit(Coalesce(quantity.code.value, quantity.unit.value, '1')) }\n else\n Message(null, true, 'FHIRHelpers.ToQuantity.InvalidFHIRQuantity', 'Error', 'Invalid FHIR Quantity code: ' & quantity.unit.value & ' (' & quantity.system.value & '|' & quantity.code.value & ')')\n end"
},
{
"url" : "displaySequence",
"valueInteger" : 39
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToCalendarUnit"
},
{
"url" : "statement",
"valueString" : "define function ToCalendarUnit(unit System.String):\n case unit\n when 'ms' then 'millisecond'\n when 's' then 'second'\n when 'min' then 'minute'\n when 'h' then 'hour'\n when 'd' then 'day'\n when 'wk' then 'week'\n when 'mo' then 'month'\n when 'a' then 'year'\n else unit\n end"
},
{
"url" : "displaySequence",
"valueInteger" : 40
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToConcept"
},
{
"url" : "statement",
"valueString" : "define function ToConcept(concept FHIR.CodeableConcept):\n if concept is null then\n null\n else\n System.Concept {\n codes: concept.coding C return ToCode(C),\n display: concept.text.value\n }"
},
{
"url" : "displaySequence",
"valueInteger" : 41
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "FHIRHelpers"
},
{
"url" : "name",
"valueString" : "ToCode"
},
{
"url" : "statement",
"valueString" : "define function ToCode(coding FHIR.Coding):\n if coding is null then\n null\n else\n System.Code {\n code: coding.code.value,\n system: coding.system.value,\n version: coding.version.value,\n display: coding.display.value\n }"
},
{
"url" : "displaySequence",
"valueInteger" : 42
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "WHOCommon"
},
{
"url" : "name",
"valueString" : "mostRecent"
},
{
"url" : "statement",
"valueString" : "define fluent function mostRecent(immunizations List<Immunization>):\n Last(\n immunizations I\n sort by start of occurrence.toInterval()\n )"
},
{
"url" : "displaySequence",
"valueInteger" : 43
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZCommon"
},
{
"url" : "name",
"valueString" : "seriesBooster"
},
{
"url" : "statement",
"valueString" : "/**\n * @description: Gets the doses from the Booster series\n */\ndefine fluent function seriesBooster(immunizations List<Immunization>):\n immunizations I where\n exists( I.protocolApplied pa where pa.series = 'Booster dose' )"
},
{
"url" : "displaySequence",
"valueInteger" : 44
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
},
{
"extension" : [
{
"url" : "libraryName",
"valueString" : "IMMZCommon"
},
{
"url" : "name",
"valueString" : "getDose"
},
{
"url" : "statement",
"valueString" : "/**\n * @description: Gets a given immunization from a list that matches the dose number\n */\ndefine fluent function getDose(immunization Immunization, doseNumber String):\n immunization I where\n exists( I.protocolApplied pa where pa.doseNumber = doseNumber )"
},
{
"url" : "displaySequence",
"valueInteger" : 45
}
],
"url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
}
],
"name" : "EffectiveDataRequirements",
"status" : "active",
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/library-type",
"code" : "module-definition"
}
]
},
"relatedArtifact" : [
{
"type" : "depends-on",
"display" : "FHIR model information",
"resource" : "http://fhir.org/guides/cqf/common/Library/FHIR-ModelInfo|4.0.1"
},
{
"type" : "depends-on",
"display" : "Library Encounter",
"resource" : "http://smart.who.int/immunizations/Library/IMMZD2DTCholeraEncounterElements"
},
{
"type" : "depends-on",
"display" : "Library Common",
"resource" : "http://smart.who.int/immunizations/Library/IMMZCommon"
},
{
"type" : "depends-on",
"display" : "Library FHIRHelpers",
"resource" : "http://fhir.org/guides/cqf/common/Library/FHIRHelpers|4.0.1"
},
{
"type" : "depends-on",
"display" : "Library Encounter",
"resource" : "http://smart.who.int/immunizations/Library/IMMZEncounterElements"
},
{
"type" : "depends-on",
"display" : "Library Elements",
"resource" : "http://smart.who.int/immunizations/Library/IMMZElements"
},
{
"type" : "depends-on",
"display" : "Library WC",
"resource" : "http://smart.who.int/immunizations/Library/WHOCommon"
},
{
"type" : "depends-on",
"display" : "Library Concepts",
"resource" : "http://smart.who.int/immunizations/Library/IMMZConcepts"
},
{
"type" : "depends-on",
"display" : "Value set Cholera vaccines",
"resource" : "http://smart.who.int/immunizations/ValueSet/IMMZ.Z.DE2"
}
],
"parameter" : [
{
"name" : "Today",
"use" : "in",
"min" : 0,
"max" : "1",
"type" : "date"
},
{
"name" : "Cholera dose 2 Create",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "string"
},
{
"name" : "Cholera dose 2",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "boolean"
},
{
"name" : "Cholera booster dose 1 Create",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "string"
},
{
"name" : "Cholera booster dose 2",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "boolean"
},
{
"name" : "Cholera dose 1",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "boolean"
},
{
"name" : "Cholera booster dose 1",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "boolean"
},
{
"name" : "Cholera booster dose 2 Create",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "string"
},
{
"name" : "Cholera dose 1 Create",
"use" : "out",
"min" : 0,
"max" : "1",
"type" : "string"
}
],
"dataRequirement" : [
{
"type" : "Immunization",
"profile" : [
🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
],
"mustSupport" : [
"status",
"isSubpotent",
"protocolApplied",
"occurrence"
],
"codeFilter" : [
{
"path" : "status",
"code" : [
{
"code" : "completed"
}
]
}
]
},
{
"type" : "Immunization",
"profile" : [
🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
],
"mustSupport" : [
"occurrence",
"protocolApplied"
]
},
{
"type" : "Immunization",
"profile" : [
🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
],
"mustSupport" : [
"status",
"isSubpotent",
"occurrence",
"vaccineCode",
"protocolApplied"
],
"codeFilter" : [
{
"path" : "status",
"code" : [
{
"code" : "completed"
}
]
},
{
"path" : "vaccineCode",
"valueSet" : "http://smart.who.int/immunizations/ValueSet/IMMZ.Z.DE2"
}
]
},
{
"type" : "Patient",
"profile" : [
🔗 "http://hl7.org/fhir/StructureDefinition/Patient"
],
"mustSupport" : [
"birthDate"
]
}
]
}
],
"extension" : [
{
"url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
"valueCode" : "computable"
},
{
"url" : "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-effectiveDataRequirements",
"valueCanonical" : "#effective-data-requirements"
}
],
"url" : "http://smart.who.int/immunizations/PlanDefinition/IMMZD18SCholeraWCVaccines",
"version" : "1.0.0",
"name" : "IMMZD18SCholeraWCVaccines",
"title" : "IMMZ.D18.S.Cholera.WC vaccines schedule",
"type" : {
"coding" : [
{
"system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
"code" : "eca-rule"
}
]
},
"status" : "draft",
"experimental" : false,
"date" : "2026-03-31T13:54:17+00:00",
"publisher" : "WHO",
"contact" : [
{
"name" : "WHO",
"telecom" : [
{
"system" : "url",
"value" : "http://who.int"
}
]
}
],
"description" : "IMMZ.D18.S.Cholera.WC vaccines schedule\nWhole-cell (WC) vaccines (Shanchol, Euvchol and mORCVAX), 2-dose schedule",
"relatedArtifact" : [
{
"type" : "citation",
"citation" : "WHO recommendations for routine immunization - summary tables (January 2025)"
}
],
"library" : [
🔗 "http://smart.who.int/immunizations/Library/IMMZD18SCholeraWCVaccinesLogic"
],
"action" : [
{
"title" : "Cholera dose 1",
"description" : "Provision of the cholera dose 1\nTrigger event: Child's birth and no cholera doses have been administered\nTrigger pseudo: Child's birth AND Count of vaccines administered (where \"Vaccine type\" = \"Cholera vaccines\" and \"Type of dose\" = \"Primary series\") = 0\nTrigger date: \"Date of birth\"\nOR\nLatest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\")\nCreate condition: WC vaccines: 2 doses should be given 14 days apart to individuals aged ≥ 1 year.\nRevaccination is recommended where there is continued risk of Vibrio cholerae infection. For WC vaccines, revaccination is recommended after 3 years.",
"condition" : [
{
"kind" : "applicability",
"expression" : {
"description" : "Cholera dose 1",
"language" : "text/cql-identifier",
"expression" : "Cholera dose 1"
}
}
],
"definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
"dynamicValue" : [
{
"path" : "status",
"expression" : {
"language" : "text/cql-expression",
"expression" : "'active'"
}
},
{
"path" : "payload.contentString",
"expression" : {
"language" : "text/cql-identifier",
"expression" : "Cholera dose 1 Create"
}
},
{
"path" : "category.coding",
"expression" : {
"description" : "Category of communication",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"
}
},
{
"path" : "priority",
"expression" : {
"description" : "Alert priority",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
}
}
]
},
{
"title" : "Cholera dose 2",
"description" : "Provision of the cholera dose 2\nTrigger event: First cholera dose administered\nTrigger pseudo: Latest \"Dose number\" (where \"Vaccine type\" = \"Cholera vaccines\"and \"Type of dose\" = \"Primary series\") = 1\nTrigger date: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Cholera vaccines\")\nCreate condition: WC vaccines: 2 doses should be given 14 days apart to individuals aged ≥ 1 year.",
"condition" : [
{
"kind" : "applicability",
"expression" : {
"description" : "Cholera dose 2",
"language" : "text/cql-identifier",
"expression" : "Cholera dose 2"
}
}
],
"definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
"dynamicValue" : [
{
"path" : "status",
"expression" : {
"language" : "text/cql-expression",
"expression" : "'active'"
}
},
{
"path" : "payload.contentString",
"expression" : {
"language" : "text/cql-identifier",
"expression" : "Cholera dose 2 Create"
}
},
{
"path" : "category.coding",
"expression" : {
"description" : "Category of communication",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"
}
},
{
"path" : "priority",
"expression" : {
"description" : "Alert priority",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
}
}
]
},
{
"title" : "Cholera booster dose 1",
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"condition" : [
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"kind" : "applicability",
"expression" : {
"description" : "Cholera booster dose 1",
"language" : "text/cql-identifier",
"expression" : "Cholera booster dose 1"
}
}
],
"definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
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"expression" : {
"language" : "text/cql-expression",
"expression" : "'active'"
}
},
{
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"expression" : {
"language" : "text/cql-identifier",
"expression" : "Cholera booster dose 1 Create"
}
},
{
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"expression" : {
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"language" : "text/cql-expression",
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}
},
{
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"expression" : {
"description" : "Alert priority",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
}
}
]
},
{
"title" : "Cholera booster dose 2",
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{
"kind" : "applicability",
"expression" : {
"description" : "Cholera booster dose 2",
"language" : "text/cql-identifier",
"expression" : "Cholera booster dose 2"
}
}
],
"definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
"dynamicValue" : [
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"expression" : {
"language" : "text/cql-expression",
"expression" : "'active'"
}
},
{
"path" : "payload.contentString",
"expression" : {
"language" : "text/cql-identifier",
"expression" : "Cholera booster dose 2 Create"
}
},
{
"path" : "category.coding",
"expression" : {
"description" : "Category of communication",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"
}
},
{
"path" : "priority",
"expression" : {
"description" : "Alert priority",
"language" : "text/cql-expression",
"expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
}
}
]
}
]
}