WHO Immunization Implementation Guide
0.2.0 - ci-build

WHO Immunization Implementation Guide, published by WHO. This guide is not an authorized publication; it is the continuous build for version 0.2.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/WorldHealthOrganization/smart-immunizations/tree/123/merge and changes regularly. See the Directory of published versions

: IMMZ.D2.DT.Typhoid.Ty21a - XML Representation

Draft as of 2026-03-03

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<PlanDefinition xmlns="http://hl7.org/fhir">
  <id value="IMMZD2DTTyphoidTy21a"/>
  <meta>
    <profile
             value="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-recommendationdefinition"/>
    <profile
             value="http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableplandefinition"/>
    <profile
             value="http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-publishableplandefinition"/>
  </meta>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
<div>
    <table class="grid dict">
        
        <tr>
            <th scope="row"><b>Id: </b></th>
            <td style="padding-left: 4px;">IMMZD2DTTyphoidTy21a</td>
        </tr>
        

        
        <tr>
            <th scope="row"><b>Url: </b></th>
            <td style="padding-left: 4px;"><a href="PlanDefinition-IMMZD2DTTyphoidTy21a.html">IMMZ.D2.DT.Typhoid.Ty21a</a></td>
        </tr>
        

        
        <tr>
            <th scope="row"><b>Version: </b></th>
            <td style="padding-left: 4px;">0.2.0</td>
        </tr>
        

        

        
        <tr>
            <th scope="row"><b>Title: </b></th>
            <td style="padding-left: 4px;">IMMZ.D2.DT.Typhoid.Ty21a</td>
        </tr>
        

        

        
        <tr>
            <th scope="row"><b>Status: </b></th>
            <td style="padding-left: 4px;">draft</td>
        </tr>
        

        

        
        <tr>
            <th scope="row"><b>Type: </b></th>
            <td style="padding-left: 4px;">
                
                    
                        
                        <p style="margin-bottom: 5px;">
                            <b>system: </b> <span><a href="http://terminology.hl7.org/7.0.1/CodeSystem-plan-definition-type.html">http://terminology.hl7.org/CodeSystem/plan-definition-type</a></span>
                        </p>
                        
                        
                        <p style="margin-bottom: 5px;">
                            <b>code: </b> <span>eca-rule</span>
                        </p>
                        
                        
                    
                
                
            </td>
        </tr>
        

        

        
        <tr>
            <th scope="row"><b>Date: </b></th>
            <td style="padding-left: 4px;">2026-03-03 13:07:11+0000</td>
        </tr>
        

        
        <tr>
            <th scope="row"><b>Publisher: </b></th>
            <td style="padding-left: 4px;">WHO</td>
        </tr>
        

        
        <tr>
            <th scope="row"><b>Description: </b></th>
            <td style="padding-left: 4px;"><div><p>IMMZ.D2.DT.Typhoid.Ty21a
Live attenuated Ty21a vaccine schedule</p>
</div></td>
        </tr>
        

        
        <tr>
            <th scope="row"><b>Knowledge Capability: </b></th>
            <td style="padding-left: 4px;">
                
                computable 
            </td>
        </tr>
        

        

        

        

        

        

        

        

        

        

        
        <tr>
            <th scope="row"><b>Related Artifacts: </b></th>
            <td style="padding-left: 4px;">
                
                
                <p><b>References</b></p>
                <ul>
                    
                    <li><div><p>WHO recommendations for routine immunization - summary tables (January 2025)</p>
</div><br/><a href="null"/></li>
                    
                </ul>
                
                
                
                
                
                
            </td>
        </tr>
        

        
        <tr>
            <th scope="row"><b>Libraries: </b></th>
            <td style="padding-left: 4px;">
                <table class="grid-dict">
                    
                    <tr>
                        <td><a href="Library-IMMZD2DTTyphoidTy21aLogic.html">IMMZD2DTTyphoidTy21aLogic</a></td>
                    </tr>
                    
                </table>
            </td>
        </tr>
        

        
        <tr>
            <th scope="row"><b>Actions: </b></th>
            <td style="padding-left: 4px;">
                <table class="grid-dict">
                    
                    <tr>
                        <td>
                            
                            <b> Determine if the client is due for Typhoid.:</b> Determine if the client is due for Typhoid vaccine according to the national immunization protocol.
Live attenuated Ty21a vaccine schedule
                            
                            <br/>
                            
                            
                            <b>If:</b>
                            
                            <i>Applicability:</i>
                            
                            Client is due for Typhoid vaccination
                            
                            <i>(Client is due for Typhoid vaccination)</i>
                            <br/>
                            
                            
                            
                            
                            <b>Then:</b> <i>Definition:</i> <a href="ActivityDefinition-IMMZD2DTMR.html">IMMZD2DTMR</a><br/>
                            
                            <i>Dynamic Values:</i><br/>
                            
                            status: <i>('draft')</i>
                            <br/>
                            
                            intent: <i>('proposal')</i>
                            <br/>
                            
                            medication: <i>(Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE21', display: 'Typhoid vaccines' } }, display: 'Typhoid vaccines' })</i>
                            <br/>
                            
                            
                            
                            
                        </td>
                    </tr>
                    
                    <tr>
                        <td>
                            
                            <b> Determine if the client is due for Typhoid.:</b> Determine if the client is due for Typhoid vaccine according to the national immunization protocol.
Live attenuated Ty21a vaccine schedule
                            
                            <br/>
                            
                            
                            <b>If:</b>
                            
                            <i>Applicability:</i>
                            
                            Client is due for typhoid booster dose
                            
                            <i>(Client is due for typhoid booster dose)</i>
                            <br/>
                            
                            
                            
                            
                            <b>Then:</b> <i>Definition:</i> <a href="ActivityDefinition-IMMZD2DTMR.html">IMMZD2DTMR</a><br/>
                            
                            <i>Dynamic Values:</i><br/>
                            
                            status: <i>('draft')</i>
                            <br/>
                            
                            intent: <i>('proposal')</i>
                            <br/>
                            
                            medication: <i>(Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE21', display: 'Typhoid vaccines' } }, display: 'Typhoid vaccines' })</i>
                            <br/>
                            
                            
                            
                            
                        </td>
                    </tr>
                    
                    <tr>
                        <td>
                            
                            <b> Check for Guidance for the patient regarding IMMZ.D2.DT.Typhoid.Ty21a.:</b> Show Guidance for the patient regarding IMMZ.D2.DT.Typhoid.Ty21a.
                            
                            <br/>
                            
                            
                            <b>If:</b>
                            
                            <i>Applicability:</i>
                            
                            Has Guidance
                            
                            <i>(Has Guidance)</i>
                            <br/>
                            
                            
                            
                            
                            <b>Then:</b> <i>Definition:</i> <a href="ActivityDefinition-IMMZD2DTCR.html">IMMZ.D2.DT.CR</a><br/>
                            
                            <i>Dynamic Values:</i><br/>
                            
                            status: <i>('active')</i>
                            <br/>
                            
                            payload.contentString: <i>(Guidance)</i>
                            <br/>
                            
                            category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>
                            <br/>
                            
                            priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>
                            <br/>
                            
                            
                            
                            
                        </td>
                    </tr>
                    
                </table>
            </td>
        </tr>
        
    </table>
</div>
</div>
  </text>
  <contained>
    <Library>
      <id value="effective-data-requirements"/>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-directReferenceCode">
        <valueCoding>
          <system
                  value="http://smart.who.int/immunizations/CodeSystem/IMMZ.D"/>
          <code value="DE203"/>
          <display value="Completed the primary vaccination series"/>
        </valueCoding>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Current Patient Age In Years"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/** 
 * @dataElement Patient age in years
 */
define &quot;Current Patient Age In Years&quot;:
  AgeInYearsAt(Today)"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="0"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Client's age is less than 6 years"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: Client's age is less than 6 years
@pseudocode: Today's date − &quot;Date of birth&quot; &lt; 6 years
@code: Client's age is less than 6 years-40
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;Client's age is less than 6 years&quot;:
  Encounter.&quot;Current Patient Age In Years&quot; &lt; 6"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="1"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is not due for Typhoid vaccination Case 1"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for Typhoid vaccination Case 1
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Not due&quot;
*/
define &quot;Client is not due for Typhoid vaccination Case 1&quot;:
  Encounter.&quot;Client's age is less than 6 years&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="2"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Client's age is more than or equal to 6 years"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: Client's age is more than or equal to 6 years
@pseudocode: Today's date − &quot;Date of birth&quot; ≥ 6 years
@code: Client's age is more than or equal to 6 years-40
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;Client's age is more than or equal to 6 years&quot;:
  Encounter.&quot;Current Patient Age In Years&quot; &gt;= 6"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="3"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZElements"/>
        </extension>
        <extension url="name">
          <valueString value="Doses Administered to Patient"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/**
 * @dataElement All Doses Administered to Patient
 */
define &quot;Doses Administered to Patient&quot;:
  [Immunization] I
    where I.status = 'completed'
    and I.isSubpotent is not true"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="4"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Doses Administered to Patient"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/**
 * @dataElement All Doses Administered to Patient
 */
define &quot;Doses Administered to Patient&quot;:
  Elements.&quot;Doses Administered to Patient&quot; I
    where I.occurrence.toInterval() same day or before Today"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="5"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Typhoid Doses Administered to Patient"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@internal: Typhoid containing Doses Administered to Patient
*/
define &quot;Typhoid Doses Administered to Patient&quot;:
  Encounter.&quot;Doses Administered to Patient&quot; I
  where
    I.vaccineCode in Concepts.&quot;Typhoid vaccines&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="6"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Typhoid Primary Series Doses Administered to Patient"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@internal: Typhoid containing Doses Administered to Patient that are in the Primary series
*/
define &quot;Typhoid Primary Series Doses Administered to Patient&quot;:
  &quot;Typhoid Doses Administered to Patient&quot;.seriesPrimary()"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="7"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Number of Typhoid Primary Series Doses Administered"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@internal: Number of Typhoid Primary Series doses
*/
define &quot;Number of Typhoid Primary Series Doses Administered&quot;:
  Count(&quot;Typhoid Primary Series Doses Administered to Patient&quot;)"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="8"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="One typhoid primary series dose was administered"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: One typhoid primary series dose was administered
@pseudocode: Count of vaccines administered (where &quot;Vaccine type&quot; = &quot;Typhoid vaccines&quot; and &quot;Type of dose&quot; = &quot;Primary series&quot;) = 1
@code: One typhoid primary series dose was administered-116
@decision: IMMZ.D2.DT.Typhoid.TCV: Typhoid conjugate vaccine (TCV) schedule
@decision: IMMZ.D2.DT.Typhoid.ViPS: Unconjugated Vi polysaccharide (ViPS) schedule
*/
define &quot;One typhoid primary series dose was administered&quot;:
  &quot;Number of Typhoid Primary Series Doses Administered&quot; = 1"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="9"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Completed the primary vaccination series Observation"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@internal: Completed the primary vaccination series Observation
*/
define &quot;Completed the primary vaccination series Observation&quot;:
  ([Observation: Concepts.&quot;Completed the primary vaccination series&quot;]).complete()"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="10"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Completed the primary vaccination series Observation"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@internal: Completed the primary vaccination series Observation
*/
define &quot;Completed the primary vaccination series Observation&quot;:
  Elements.&quot;Completed the primary vaccination series Observation&quot;.encounterOrOnBefore(EncounterId, Today)"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="11"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Primary series is complete"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: Primary series is complete
@pseudocode: &quot;Completed the primary vaccination series&quot; (where &quot;Vaccine type&quot; = &quot;Typhoid vaccines&quot;) = TRUE
@code: Primary series is complete-93
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;Primary series is complete&quot;:
  &quot;One typhoid primary series dose was administered&quot;
  or Coalesce(
    &quot;Typhoid Doses Administered to Patient&quot; Dose
    aggregate Result: Encounter.&quot;Completed the primary vaccination series Observation&quot;.partOf.references(Dose) or Result,
    false )"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="12"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Primary series is not complete"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: Primary series is not complete
@pseudocode: &quot;Completed the primary vaccination series&quot; (where &quot;Vaccine type&quot; = &quot;Typhoid vaccines&quot;) ≠ TRUE
@code: Primary series is not complete-93
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;Primary series is not complete&quot;:
  not &quot;Primary series is complete&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="13"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZElements"/>
        </extension>
        <extension url="name">
          <valueString value="Live Attenuated Vaccines"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
  @dataElement: Live attenuated vaccines
*/
define &quot;Live Attenuated Vaccines&quot;:
  &quot;Doses Administered to Patient&quot; I 
    where I.vaccineCode in Concepts.&quot;Live Attenuated&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="14"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Live Attenuated Vaccines"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@dataElement Live attenuated vaccines
*/
define &quot;Live Attenuated Vaccines&quot;:
  Elements.&quot;Live Attenuated Vaccines&quot; I
    where I.occurrence.toInterval() same day or before Today"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="15"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Date of Latest Live Attenuated Vaccine"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@dataElement Date and time of last live attenuated vaccine
*/
define &quot;Date of Latest Live Attenuated Vaccine&quot;:
  date from start of &quot;Live Attenuated Vaccines&quot;.mostRecent().occurrence.toInterval()"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="16"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Live vaccine was administered in the last 4 weeks"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: Live vaccine was administered in the last 4 weeks
@pseudocode: Today's date − latest &quot;Date and time of vaccination&quot; (where &quot;Live vaccine&quot; = TRUE) &lt; 4 weeks
*/
define &quot;Live vaccine was administered in the last 4 weeks&quot;:
	&quot;Date of Latest Live Attenuated Vaccine&quot; is not null 
    and duration in weeks between &quot;Date of Latest Live Attenuated Vaccine&quot; and Today &lt; 4"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="17"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Live vaccine, other than typhoid, was administered in the past 4 weeks"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: Live vaccine, other than typhoid, was administered in the past 4 weeks
@pseudocode: Today's date − latest &quot;Date and time of vaccination&quot; (where &quot;Live vaccine&quot; = TRUE AND &quot;Vaccine type&quot; ≠ &quot;Typhoid vaccines&quot;) &lt; 4 weeks
@code: Live vaccine, other than typhoid, was administered in the past 4 weeks-132
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;Live vaccine, other than typhoid, was administered in the past 4 weeks&quot;:
  Encounter.&quot;Live vaccine was administered in the last 4 weeks&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="18"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is not due for Typhoid vaccination Case 2"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for Typhoid vaccination Case 2
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Not due&quot;
*/
define &quot;Client is not due for Typhoid vaccination Case 2&quot;:
  Encounter.&quot;Client's age is more than or equal to 6 years&quot;
    and Encounter.&quot;Primary series is not complete&quot;
    and Encounter.&quot;Live vaccine, other than typhoid, was administered in the past 4 weeks&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="19"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString value="Client is not due for Typhoid vaccination"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for Typhoid vaccination
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Not due&quot;
*/
define &quot;Client is not due for Typhoid vaccination&quot;:
  &quot;Client is not due for Typhoid vaccination Case 1&quot;
    or &quot;Client is not due for Typhoid vaccination Case 2&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="20"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is not due for Typhoid vaccination Guidance"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for Typhoid vaccination Guidance
@guidance = Should not vaccinate client with typhoid dose as client's age is less than 6 years.
Check for any other vaccines due and inform the caregiver of when to come back for the first dose.
@guidance = Should not vaccinate client with typhoid dose as live vaccine was administered in the past 4 weeks.
Check for other vaccines due and inform the caregiver or the client when the next dose should be administered.
*/
define &quot;Client is not due for Typhoid vaccination Guidance&quot;:
  case
    when &quot;Client is not due for Typhoid vaccination Case 1&quot; then 'Should not vaccinate client with typhoid dose as client\'s age is less than 6 years.
Check for any other vaccines due and inform the caregiver of when to come back for the first dose.'
    when &quot;Client is not due for Typhoid vaccination Case 2&quot; then 'Should not vaccinate client with typhoid dose as live vaccine was administered in the past 4 weeks.
Check for other vaccines due and inform the caregiver or the client when the next dose should be administered.'
    else ''
  end"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="21"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="No live vaccine was administered in the last 4 weeks"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: No live vaccine was administered in the last 4 weeks
@pseudocode: Today's date − latest &quot;Date and time of vaccination&quot; (where &quot;Live vaccine&quot; = TRUE) ≥ 4 weeks
*/
define &quot;No live vaccine was administered in the last 4 weeks&quot;:
  not(&quot;Live vaccine was administered in the last 4 weeks&quot;)"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="22"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="No live vaccine, other than typhoid, was administered in the past 4 weeks"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: No live vaccine, other than typhoid, was administered in the past 4 weeks
@pseudocode: Today's date − latest &quot;Date and time of vaccination&quot; (where &quot;Live vaccine&quot; = TRUE AND &quot;Vaccine type&quot; ≠ &quot;Typhoid vaccines&quot;) ≥ 4 weeks
@code: No live vaccine, other than typhoid, was administered in the past 4 weeks-132
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;No live vaccine, other than typhoid, was administered in the past 4 weeks&quot;:
  Encounter.&quot;No live vaccine was administered in the last 4 weeks&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="23"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString value="Client is due for Typhoid vaccination"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is due for Typhoid vaccination
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Due&quot;
*/
define &quot;Client is due for Typhoid vaccination&quot;:
  Encounter.&quot;Client's age is more than or equal to 6 years&quot;
    and Encounter.&quot;Primary series is not complete&quot;
    and Encounter.&quot;No live vaccine, other than typhoid, was administered in the past 4 weeks&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="24"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is due for Typhoid vaccination Guidance"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is due for Typhoid vaccination Guidance
@guidance: Prescribe the Ty21a primary series (if not done yet). Should vaccinate client with typhoid dose as primary series has not been completed and no live vaccines was administered in the past 4 weeks.
Check for contraindications.
*/
define &quot;Client is due for Typhoid vaccination Guidance&quot;:
  'Prescribe the Ty21a primary series (if not done yet). Should vaccinate client with typhoid dose as primary series has not been completed and no live vaccines was administered in the past 4 weeks.
Check for contraindications.'"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="25"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString value="Date of Latest Typhoid Dose"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@internal: Date of Latest Typhoid Dose
*/
define &quot;Date of Latest Typhoid Dose&quot;:
  date from start of &quot;Typhoid Doses Administered to Patient&quot;.mostRecent().occurrence.toInterval()"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="26"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="The latest typhoid dose was administered less than 3 years ago"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: The latest typhoid dose was administered less than 3 years ago
@pseudocode: Today's date − latest &quot;Date and time of vaccination&quot; (where &quot;Vaccine type&quot; = &quot;Typhoid vaccines&quot;) &lt; 3 years
@code: The latest typhoid dose was administered less than 3 years ago-106
@decision: IMMZ.D2.DT.Typhoid.ViPS: Unconjugated Vi polysaccharide (ViPS) schedule
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;The latest typhoid dose was administered less than 3 years ago&quot;:
  &quot;Date of Latest Typhoid Dose&quot; is not null
    and duration in years between &quot;Date of Latest Typhoid Dose&quot; and Today &lt; 3"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="27"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is not due for typhoid booster dose Case 1"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for typhoid booster dose Case 1
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Not due&quot;
*/
define &quot;Client is not due for typhoid booster dose Case 1&quot;:
  Encounter.&quot;Client's age is more than or equal to 6 years&quot;
    and Encounter.&quot;Primary series is complete&quot;
    and Encounter.&quot;The latest typhoid dose was administered less than 3 years ago&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="28"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidEncounterElements"/>
        </extension>
        <extension url="name">
          <valueString
                       value="The latest typhoid dose was administered more than 3 years ago"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@input: The latest typhoid dose was administered more than 3 years ago
@pseudocode: Today's date − latest &quot;Date and time of vaccination&quot; (where &quot;Vaccine type&quot; = &quot;Typhoid vaccines&quot;) ≥ 3 years
@code: The latest typhoid dose was administered more than 3 years ago-106
@decision: IMMZ.D2.DT.Typhoid.ViPS: Unconjugated Vi polysaccharide (ViPS) schedule
@decision: IMMZ.D2.DT.Typhoid.Ty21a: Live attenuated Ty21a vaccine schedule
*/
define &quot;The latest typhoid dose was administered more than 3 years ago&quot;:
  not &quot;The latest typhoid dose was administered less than 3 years ago&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="29"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is not due for typhoid booster dose Case 2"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for typhoid booster dose Case 2
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Not due&quot;
*/
define &quot;Client is not due for typhoid booster dose Case 2&quot;:
  Encounter.&quot;Client's age is more than or equal to 6 years&quot;
    and Encounter.&quot;Primary series is complete&quot;
    and Encounter.&quot;The latest typhoid dose was administered more than 3 years ago&quot;
    and Encounter.&quot;Live vaccine, other than typhoid, was administered in the past 4 weeks&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="30"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString value="Client is not due for typhoid booster dose"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for typhoid booster dose
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Not due&quot;
*/
define &quot;Client is not due for typhoid booster dose&quot;:
  &quot;Client is not due for typhoid booster dose Case 1&quot;
    or &quot;Client is not due for typhoid booster dose Case 2&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="31"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is not due for typhoid booster dose Guidance"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is not due for typhoid booster dose Guidance
@guidance = Should not vaccinate client with typhoid booster dose as the latest typhoid dose was administered less than 3 years ago.
Check for any other vaccines due and inform the caregiver or the client when the next dose should be administered.
@guidance = Should not vaccinate client with typhoid booster dose as live vaccine was administered in the past 4 weeks.
Check for any other vaccines due and inform the caregiver or the client when the next dose should be administered
*/
define &quot;Client is not due for typhoid booster dose Guidance&quot;:
  case
    when &quot;Client is not due for typhoid booster dose Case 1&quot; then 'Should not vaccinate client with typhoid booster dose as the latest typhoid dose was administered less than 3 years ago.
Check for any other vaccines due and inform the caregiver or the client when the next dose should be administered.'
    when &quot;Client is not due for typhoid booster dose Case 2&quot; then 'Should not vaccinate client with typhoid booster dose as live vaccine was administered in the past 4 weeks.
Check for any other vaccines due and inform the caregiver or the client when the next dose should be administered'
    else ''
  end"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="32"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString value="Client is due for typhoid booster dose"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is due for typhoid booster dose
@pseudocode: &quot;Immunization recommendation status&quot; = &quot;Due&quot;
*/
define &quot;Client is due for typhoid booster dose&quot;:
  Encounter.&quot;Client's age is more than or equal to 6 years&quot;
    and Encounter.&quot;Primary series is complete&quot;
    and Encounter.&quot;The latest typhoid dose was administered more than 3 years ago&quot;
    and Encounter.&quot;No live vaccine, other than typhoid, was administered in the past 4 weeks&quot;"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="33"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString
                       value="Client is due for typhoid booster dose Guidance"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@output: Client is due for typhoid booster dose Guidance
@guidance: Prescribe the Ty21a booster series. Should vaccinate client with typhoid booster dose as primary series has been completed, the latest typhoid dose was administered more than 3 years ago and no live vaccine was administered in the past 4 weeks.
Check for contraindications.
*/
define &quot;Client is due for typhoid booster dose Guidance&quot;:
  'Prescribe the Ty21a booster series. Should vaccinate client with typhoid booster dose as primary series has been completed, the latest typhoid dose was administered more than 3 years ago and no live vaccine was administered in the past 4 weeks.
Check for contraindications.'"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="34"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString value="Guidance"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@dynamicValue: Guidance
*/
define &quot;Guidance&quot;:
  case 
    when &quot;Client is not due for Typhoid vaccination&quot; then &quot;Client is not due for Typhoid vaccination Guidance&quot;
    when &quot;Client is due for Typhoid vaccination&quot; then &quot;Client is due for Typhoid vaccination Guidance&quot;
    when &quot;Client is not due for typhoid booster dose&quot; then &quot;Client is not due for typhoid booster dose Guidance&quot;
    when &quot;Client is due for typhoid booster dose&quot; then &quot;Client is due for typhoid booster dose Guidance&quot; 
    else ''
  end"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="35"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZD2DTTyphoidTy21aLogic"/>
        </extension>
        <extension url="name">
          <valueString value="Has Guidance"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define &quot;Has Guidance&quot;:
  &quot;Guidance&quot; is not null and &quot;Guidance&quot; != ''"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="36"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZCommon"/>
        </extension>
        <extension url="name">
          <valueString value="seriesPrimary"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/**
 * @description: Gets the doses from the primary series
 */
define fluent function seriesPrimary(immunizations List&lt;Immunization&gt;):
  immunizations I where
    exists( I.protocolApplied pa where pa.series = 'Primary series' )"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="37"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="FHIRHelpers"/>
        </extension>
        <extension url="name">
          <valueString value="ToString"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define function ToString(value string): value.value"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="38"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="FHIRHelpers"/>
        </extension>
        <extension url="name">
          <valueString value="ToString"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define function ToString(value ImmunizationStatus): value.value"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="39"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="FHIRHelpers"/>
        </extension>
        <extension url="name">
          <valueString value="ToBoolean"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define function ToBoolean(value boolean): value.value"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="40"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="FHIRHelpers"/>
        </extension>
        <extension url="name">
          <valueString value="ToConcept"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define function ToConcept(concept FHIR.CodeableConcept):
    if concept is null then
        null
    else
        System.Concept {
            codes: concept.coding C return ToCode(C),
            display: concept.text.value
        }"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="41"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="FHIRHelpers"/>
        </extension>
        <extension url="name">
          <valueString value="ToCode"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define function ToCode(coding FHIR.Coding):
    if coding is null then
        null
    else
        System.Code {
          code: coding.code.value,
          system: coding.system.value,
          version: coding.version.value,
          display: coding.display.value
        }"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="42"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="WHOCommon"/>
        </extension>
        <extension url="name">
          <valueString value="references"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@description: Returns true if any of the given references are to the given resource
@comment: Returns true if the `id` element of the given resource exactly equals the tail of any of the given references.
NOTE: This function assumes resources from the same source server.
*/
define fluent function references(references List&lt;FHIR.Reference&gt;, resource FHIR.Resource):
  exists (references R where R.references(resource))"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="43"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="WHOCommon"/>
        </extension>
        <extension url="name">
          <valueString value="references"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@description: Returns true if the given reference is to the given resource
@comment: Returns true if the `id` element of the given resource exactly equals the tail of the given reference.
NOTE: This function assumes resources from the same source server.
*/
define fluent function references(reference FHIR.Reference, resource FHIR.Resource):
  resource.id = Last(Split(reference.reference, '/'))"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="44"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="IMMZCommon"/>
        </extension>
        <extension url="name">
          <valueString value="encounterOrOnBefore"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/**
 * @description: Gets observation from an encounter or on or before a date
 */
define fluent function encounterOrOnBefore(observations List&lt;Observation&gt;, EncounterId String, beforeDate Date):
  observations O where
    (O.encounter.references(EncounterId)
      or O.effective.toInterval() starts same day or before beforeDate)"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="45"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="WHOCommon"/>
        </extension>
        <extension url="name">
          <valueString value="references"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="/*
@description: Returns true if the given reference is to the given resourceId
@comment: Returns true if the `resourceId` parameter exactly equals the tail of the given reference.
NOTE: This function assumes resources from the same source server.
*/
define fluent function references(reference FHIR.Reference, resourceId String):
  resourceId = Last(Split(reference.reference, '/'))"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="46"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="WHOCommon"/>
        </extension>
        <extension url="name">
          <valueString value="complete"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define fluent function complete(observations List&lt;Observation&gt;):
  observations O where O.status in { 'final', 'amended', 'corrected' }"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="47"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="FHIRHelpers"/>
        </extension>
        <extension url="name">
          <valueString value="ToString"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define function ToString(value ObservationStatus): value.value"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="48"/>
        </extension>
      </extension>
      <extension
                 url="http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition">
        <extension url="libraryName">
          <valueString value="WHOCommon"/>
        </extension>
        <extension url="name">
          <valueString value="mostRecent"/>
        </extension>
        <extension url="statement">
          <valueString
                       value="define fluent function mostRecent(immunizations List&lt;Immunization&gt;):
  Last(
    immunizations I
      sort by start of occurrence.toInterval()
  )"/>
        </extension>
        <extension url="displaySequence">
          <valueInteger value="49"/>
        </extension>
      </extension>
      <name value="EffectiveDataRequirements"/>
      <status value="active"/>
      <type>
        <coding>
          <system value="http://terminology.hl7.org/CodeSystem/library-type"/>
          <code value="module-definition"/>
        </coding>
      </type>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="FHIR model information"/>
        <resource
                  value="http://fhir.org/guides/cqf/common/Library/FHIR-ModelInfo|4.0.1"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Encounter"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/IMMZD2DTTyphoidEncounterElements"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Encounter"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/IMMZEncounterElements"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Common"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/IMMZCommon"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library FHIRHelpers"/>
        <resource
                  value="http://fhir.org/guides/cqf/common/Library/FHIRHelpers|4.0.1"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Elements"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/IMMZElements"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library WC"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/WHOCommon"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library FHIRHelpers"/>
        <resource
                  value="http://fhir.org/guides/cqf/common/Library/FHIRHelpers|4.0.1"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Concepts"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/IMMZConcepts"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library WC"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/WHOCommon"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Common"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/IMMZCommon"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library WC"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/WHOCommon"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Library Concepts"/>
        <resource
                  value="http://smart.who.int/immunizations/Library/IMMZConcepts"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Code system IMMZD"/>
        <resource
                  value="http://smart.who.int/immunizations/CodeSystem/IMMZ.D"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set Typhoid vaccines"/>
        <resource
                  value="http://smart.who.int/immunizations/ValueSet/IMMZ.Z.DE21"/>
      </relatedArtifact>
      <relatedArtifact>
        <type value="depends-on"/>
        <display value="Value set Live Attenuated"/>
        <resource
                  value="http://smart.who.int/immunizations/ValueSet/IMMZ.Z.LiveAttenuated"/>
      </relatedArtifact>
      <parameter>
        <name value="Today"/>
        <use value="in"/>
        <min value="0"/>
        <max value="1"/>
        <type value="date"/>
      </parameter>
      <parameter>
        <name value="EncounterId"/>
        <use value="in"/>
        <min value="0"/>
        <max value="1"/>
        <type value="string"/>
      </parameter>
      <parameter>
        <name value="Guidance"/>
        <use value="out"/>
        <min value="0"/>
        <max value="1"/>
        <type value="string"/>
      </parameter>
      <parameter>
        <name value="Has Guidance"/>
        <use value="out"/>
        <min value="0"/>
        <max value="1"/>
        <type value="boolean"/>
      </parameter>
      <parameter>
        <name value="Client is due for Typhoid vaccination"/>
        <use value="out"/>
        <min value="0"/>
        <max value="1"/>
        <type value="boolean"/>
      </parameter>
      <parameter>
        <name value="Client is due for typhoid booster dose"/>
        <use value="out"/>
        <min value="0"/>
        <max value="1"/>
        <type value="boolean"/>
      </parameter>
      <dataRequirement>
        <type value="Patient"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Patient"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
        <mustSupport value="occurrence"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
        <mustSupport value="occurrence"/>
        <mustSupport value="vaccineCode"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Observation"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Observation"/>
        <mustSupport value="code"/>
        <codeFilter>
          <path value="code"/>
          <code>
            <system
                    value="http://smart.who.int/immunizations/CodeSystem/IMMZ.D"/>
            <code value="DE203"/>
            <display value="Completed the primary vaccination series"/>
          </code>
        </codeFilter>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
        <mustSupport value="occurrence"/>
        <mustSupport value="vaccineCode"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
        <mustSupport value="vaccineCode"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
        <mustSupport value="vaccineCode"/>
        <mustSupport value="occurrence"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
        <mustSupport value="occurrence"/>
        <mustSupport value="vaccineCode"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Immunization"/>
        <profile
                 value="http://hl7.org/fhir/StructureDefinition/Immunization"/>
        <mustSupport value="status"/>
        <mustSupport value="isSubpotent"/>
        <mustSupport value="occurrence"/>
        <mustSupport value="vaccineCode"/>
      </dataRequirement>
      <dataRequirement>
        <type value="Observation"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Observation"/>
        <mustSupport value="code"/>
        <codeFilter>
          <path value="code"/>
          <code>
            <system
                    value="http://smart.who.int/immunizations/CodeSystem/IMMZ.D"/>
            <code value="DE203"/>
            <display value="Completed the primary vaccination series"/>
          </code>
        </codeFilter>
      </dataRequirement>
    </Library>
  </contained>
  <extension
             url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
    <valueCode value="computable"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-effectiveDataRequirements">
    <valueCanonical value="#effective-data-requirements"/>
  </extension>
  <url
       value="http://smart.who.int/immunizations/PlanDefinition/IMMZD2DTTyphoidTy21a"/>
  <version value="0.2.0"/>
  <name value="IMMZD2DTTyphoidTy21a"/>
  <title value="IMMZ.D2.DT.Typhoid.Ty21a"/>
  <type>
    <coding>
      <system
              value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
      <code value="eca-rule"/>
    </coding>
  </type>
  <status value="draft"/>
  <experimental value="false"/>
  <date value="2026-03-03T13:07:11+00:00"/>
  <publisher value="WHO"/>
  <contact>
    <name value="WHO"/>
    <telecom>
      <system value="url"/>
      <value value="http://who.int"/>
    </telecom>
  </contact>
  <description
               value="IMMZ.D2.DT.Typhoid.Ty21a
Live attenuated Ty21a vaccine schedule"/>
  <relatedArtifact>
    <type value="citation"/>
    <citation
              value="WHO recommendations for routine immunization - summary tables (January 2025)"/>
  </relatedArtifact>
  <library
           value="http://smart.who.int/immunizations/Library/IMMZD2DTTyphoidTy21aLogic"/>
  <action>
    <extension
               url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-rationale">
      <valueMarkdown
                     value="For Ty21a, a 3-dose oral immunization schedule, administering the vaccine every second 
  (alternate) day, is recommended above 6 years of age. If interruption between doses is &gt; 21 days, restart primary series."/>
    </extension>
    <title value="Determine if the client is due for Typhoid."/>
    <description
                 value="Determine if the client is due for Typhoid vaccine according to the national immunization protocol.
Live attenuated Ty21a vaccine schedule"/>
    <condition>
      <kind value="applicability"/>
      <expression>
        <description value="Client is due for Typhoid vaccination"/>
        <language value="text/cql-identifier"/>
        <expression value="Client is due for Typhoid vaccination"/>
      </expression>
    </condition>
    <definitionCanonical
                         value="http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTMR"/>
    <dynamicValue>
      <path value="status"/>
      <expression>
        <language value="text/cql-expression"/>
        <expression value="'draft'"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="intent"/>
      <expression>
        <language value="text/cql-expression"/>
        <expression value="'proposal'"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="medication"/>
      <expression>
        <language value="text/cql-expression"/>
        <expression
                    value="Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE21', display: 'Typhoid vaccines' } }, display: 'Typhoid vaccines' }"/>
      </expression>
    </dynamicValue>
  </action>
  <action>
    <extension
               url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-rationale">
      <valueMarkdown
                     value="Revaccination is recommended every 3–7 years for Ty21a (every 1 to 7 years for travellers from non-endemic 
  to endemic areas, depending on national policies). As a general rule, any live vaccine may be given either simultaneously 
  or at an interval of 4 weeks."/>
    </extension>
    <title value="Determine if the client is due for Typhoid."/>
    <description
                 value="Determine if the client is due for Typhoid vaccine according to the national immunization protocol.
Live attenuated Ty21a vaccine schedule"/>
    <condition>
      <kind value="applicability"/>
      <expression>
        <description value="Client is due for typhoid booster dose"/>
        <language value="text/cql-identifier"/>
        <expression value="Client is due for typhoid booster dose"/>
      </expression>
    </condition>
    <definitionCanonical
                         value="http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTMR"/>
    <dynamicValue>
      <path value="status"/>
      <expression>
        <language value="text/cql-expression"/>
        <expression value="'draft'"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="intent"/>
      <expression>
        <language value="text/cql-expression"/>
        <expression value="'proposal'"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="medication"/>
      <expression>
        <language value="text/cql-expression"/>
        <expression
                    value="Concept { codes: { Code { system: 'http://smart.who.int/immunizations/CodeSystem/IMMZ.Z', code: 'DE21', display: 'Typhoid vaccines' } }, display: 'Typhoid vaccines' }"/>
      </expression>
    </dynamicValue>
  </action>
  <action>
    <title
           value="Check for Guidance for the patient regarding IMMZ.D2.DT.Typhoid.Ty21a."/>
    <description
                 value="Show Guidance for the patient regarding IMMZ.D2.DT.Typhoid.Ty21a."/>
    <condition>
      <kind value="applicability"/>
      <expression>
        <description value="Has Guidance"/>
        <language value="text/cql-identifier"/>
        <expression value="Has Guidance"/>
      </expression>
    </condition>
    <definitionCanonical
                         value="http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR"/>
    <dynamicValue>
      <path value="status"/>
      <expression>
        <language value="text/cql-expression"/>
        <expression value="'active'"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="payload.contentString"/>
      <expression>
        <language value="text/cql-identifier"/>
        <expression value="Guidance"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="category.coding"/>
      <expression>
        <description value="Category of communication"/>
        <language value="text/cql-expression"/>
        <expression
                    value="Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"/>
      </expression>
    </dynamicValue>
    <dynamicValue>
      <path value="priority"/>
      <expression>
        <description value="Alert priority"/>
        <language value="text/cql-expression"/>
        <expression
                    value="Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"/>
      </expression>
    </dynamicValue>
  </action>
</PlanDefinition>