WHO Immunization Implementation Guide
0.2.0 - ci-build

WHO Immunization Implementation Guide, published by WHO. This guide is not an authorized publication; it is the continuous build for version 0.2.0 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/WorldHealthOrganization/smart-immunizations/tree/123/merge and changes regularly. See the Directory of published versions

: IMMZ.D18.S.Hepatitis B.4-dose schedule - JSON Representation

Draft as of 2026-03-03

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{
  "resourceType" : "PlanDefinition",
  "id" : "IMMZD18SHepatitisB4Doses",
  "meta" : {
    "profile" : [
      🔗 "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-recommendationdefinition"🔗 ,
      "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-shareableplandefinition"🔗 ,
      "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-publishableplandefinition"
    ]
  },
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n<div>\n    <table class=\"grid dict\">\n        \n        <tr>\n            <th scope=\"row\"><b>Id: </b></th>\n            <td style=\"padding-left: 4px;\">IMMZD18SHepatitisB4Doses</td>\n        </tr>\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Url: </b></th>\n            <td style=\"padding-left: 4px;\"><a href=\"PlanDefinition-IMMZD18SHepatitisB4Doses.html\">IMMZ.D18.S.Hepatitis B.4-dose schedule</a></td>\n        </tr>\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Version: </b></th>\n            <td style=\"padding-left: 4px;\">0.2.0</td>\n        </tr>\n        \n\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Title: </b></th>\n            <td style=\"padding-left: 4px;\">IMMZ.D18.S.Hepatitis B.4-dose schedule</td>\n        </tr>\n        \n\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Status: </b></th>\n            <td style=\"padding-left: 4px;\">draft</td>\n        </tr>\n        \n\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Type: </b></th>\n            <td style=\"padding-left: 4px;\">\n                \n                    \n                        \n                        <p style=\"margin-bottom: 5px;\">\n                            <b>system: </b> <span><a href=\"http://terminology.hl7.org/7.0.1/CodeSystem-plan-definition-type.html\">http://terminology.hl7.org/CodeSystem/plan-definition-type</a></span>\n                        </p>\n                        \n                        \n                        <p style=\"margin-bottom: 5px;\">\n                            <b>code: </b> <span>eca-rule</span>\n                        </p>\n                        \n                        \n                    \n                \n                \n            </td>\n        </tr>\n        \n\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Date: </b></th>\n            <td style=\"padding-left: 4px;\">2026-03-03 13:07:11+0000</td>\n        </tr>\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Publisher: </b></th>\n            <td style=\"padding-left: 4px;\">WHO</td>\n        </tr>\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Description: </b></th>\n            <td style=\"padding-left: 4px;\"><div><p>IMMZ.D18.S.Hepatitis B.4-dose schedule\n4-dose schedule (birth dose + 3 primary series doses), on-time start</p>\n</div></td>\n        </tr>\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Knowledge Capability: </b></th>\n            <td style=\"padding-left: 4px;\">\n                \n                computable \n            </td>\n        </tr>\n        \n\n        \n\n        \n\n        \n\n        \n\n        \n\n        \n\n        \n\n        \n\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Related Artifacts: </b></th>\n            <td style=\"padding-left: 4px;\">\n                \n                \n                <p><b>References</b></p>\n                <ul>\n                    \n                    <li><div><p>WHO recommendations for routine immunization - summary tables (January 2025)</p>\n</div><br/><a href=\"null\"/></li>\n                    \n                </ul>\n                \n                \n                \n                \n                \n                \n            </td>\n        </tr>\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Libraries: </b></th>\n            <td style=\"padding-left: 4px;\">\n                <table class=\"grid-dict\">\n                    \n                    <tr>\n                        <td><a href=\"Library-IMMZD18SHepatitisB4DosesLogic.html\">IMMZD18SHepatitisB4DosesLogic</a></td>\n                    </tr>\n                    \n                </table>\n            </td>\n        </tr>\n        \n\n        \n        <tr>\n            <th scope=\"row\"><b>Actions: </b></th>\n            <td style=\"padding-left: 4px;\">\n                <table class=\"grid-dict\">\n                    \n                    <tr>\n                        <td>\n                            \n                            <b> Hepatitis B dose 1:</b> Provision of hepatitis B dose 1\nTrigger event: Child's birth\nTrigger pseudo: \nTrigger date: &quot;Date of birth&quot;\nCreate condition: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.\n                            \n                            <br/>\n                            \n                            \n                            <b>If:</b>\n                            \n                            <i>Applicability:</i>\n                            \n                            Hepatitis B dose 1\n                            \n                            <i>(Hepatitis B dose 1)</i>\n                            <br/>\n                            \n                            \n                            \n                            \n                            <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n                            \n                            <i>Dynamic Values:</i><br/>\n                            \n                            status: <i>('active')</i>\n                            <br/>\n                            \n                            payload.contentString: <i>(Hepatitis B dose 1 Create)</i>\n                            <br/>\n                            \n                            category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n                            <br/>\n                            \n                            priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n                            <br/>\n                            \n                            \n                            \n                            \n                        </td>\n                    </tr>\n                    \n                    <tr>\n                        <td>\n                            \n                            <b> Hepatitis B dose 2:</b> Provision of hepatitis B dose 2\nTrigger event: First hepatitis B dose from the primary series was administered\nTrigger pseudo: Count of vaccines administered (where &quot;Vaccine type&quot; = &quot;Hepatitis B-containing vaccines&quot; and &quot;Type of dose&quot;= &quot;Primary series&quot;) = 1\nTrigger date: Latest &quot;Date and time of vaccination&quot; (where &quot;Vaccine type&quot; = &quot;Hepatitis B-containing vaccines&quot;)\nCreate condition: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.\n                            \n                            <br/>\n                            \n                            \n                            <b>If:</b>\n                            \n                            <i>Applicability:</i>\n                            \n                            Hepatitis B dose 2\n                            \n                            <i>(Hepatitis B dose 2)</i>\n                            <br/>\n                            \n                            \n                            \n                            \n                            <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n                            \n                            <i>Dynamic Values:</i><br/>\n                            \n                            status: <i>('active')</i>\n                            <br/>\n                            \n                            payload.contentString: <i>(Hepatitis B dose 2 Create)</i>\n                            <br/>\n                            \n                            category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n                            <br/>\n                            \n                            priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n                            <br/>\n                            \n                            \n                            \n                            \n                        </td>\n                    </tr>\n                    \n                    <tr>\n                        <td>\n                            \n                            <b> Hepatitis B dose 3:</b> Provision of hepatitis B dose 3\nTrigger event: Second hepatitis B dose from the primary series was administered\nTrigger pseudo: Count of vaccines administered (where &quot;Vaccine type&quot; = &quot;Hepatitis B-containing vaccines&quot; and &quot;Type of dose&quot;= &quot;Primary series&quot;) = 2\nTrigger date: Latest &quot;Date and time of vaccination&quot; (where &quot;Vaccine type&quot; = &quot;Hepatitis B-containing vaccines&quot;)\nCreate condition: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.\n                            \n                            <br/>\n                            \n                            \n                            <b>If:</b>\n                            \n                            <i>Applicability:</i>\n                            \n                            Hepatitis B dose 3\n                            \n                            <i>(Hepatitis B dose 3)</i>\n                            <br/>\n                            \n                            \n                            \n                            \n                            <b>Then:</b> <i>Definition:</i> <a href=\"ActivityDefinition-IMMZD2DTCR.html\">IMMZ.D2.DT.CR</a><br/>\n                            \n                            <i>Dynamic Values:</i><br/>\n                            \n                            status: <i>('active')</i>\n                            <br/>\n                            \n                            payload.contentString: <i>(Hepatitis B dose 3 Create)</i>\n                            <br/>\n                            \n                            category.coding: <i>(Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' })</i>\n                            <br/>\n                            \n                            priority: <i>(Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' })</i>\n                            <br/>\n                            \n                            \n                            \n                            \n                        </td>\n                    </tr>\n                    \n                </table>\n            </td>\n        </tr>\n        \n    </table>\n</div>\n</div>"
  },
  "contained" : [
    {
      "resourceType" : "Library",
      "id" : "effective-data-requirements",
      "extension" : [
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZElements"
            },
            {
              "url" : "name",
              "valueString" : "Doses Administered to Patient"
            },
            {
              "url" : "statement",
              "valueString" : "/**\n * @dataElement All Doses Administered to Patient\n */\ndefine \"Doses Administered to Patient\":\n  [Immunization] I\n    where I.status = 'completed'\n    and I.isSubpotent is not true"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 0
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBElements"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B Doses Administered to Patient"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@internal: Hepatitis B containing Doses Administered to Patient\n*/\ndefine \"Hepatitis B Doses Administered to Patient\":\n  Elements.\"Doses Administered to Patient\" I\n  where\n    I.vaccineCode in Concepts.\"Hepatitis B-containing vaccines\""
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 1
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
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        {
          "extension" : [
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              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBElements"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B Primary Series Doses Administered to Patient"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@internal: Hepatitis B containing Doses Administered to Patient that are in the Primary series\n*/\ndefine \"Hepatitis B Primary Series Doses Administered to Patient\":\n  \"Hepatitis B Doses Administered to Patient\".seriesPrimary()"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 2
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBEncounterElements"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B Primary Series Doses Administered to Patient"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@internal: Hepatitis B containing Doses Administered to Patient that are in the Primary series\n*/\ndefine \"Hepatitis B Primary Series Doses Administered to Patient\":\n  HepatitisBElements.\"Hepatitis B Primary Series Doses Administered to Patient\".onOrBefore(Today)"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 3
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBEncounterElements"
            },
            {
              "url" : "name",
              "valueString" : "Number of Hepatitis B Primary Series Doses Administered"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@internal: Number of Hepatitis B Primary Series doses\n*/\ndefine \"Number of Hepatitis B Primary Series Doses Administered\":\n  Count(\"Hepatitis B Primary Series Doses Administered to Patient\")"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 4
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBEncounterElements"
            },
            {
              "url" : "name",
              "valueString" : "One hepatitis B primary series dose was administered"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@input: One hepatitis B primary series dose was administered\n@pseudocode: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\" = \"Primary series\") = 1\n@code: One hepatitis B primary series dose was administered-131\n@decision: IMMZ.D2.DT.Hepatitis B.3 doses: 3-dose schedule (birth dose + 2 primary series doses), on-time start\n*/\ndefine \"One hepatitis B primary series dose was administered\":\n  \"Number of Hepatitis B Primary Series Doses Administered\" = 1"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 5
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "First hepatitis B dose from the primary series was administered"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@complete: First hepatitis B dose from the primary series was administered\n@pseudocode: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\"= \"Primary series\") = 1\n*/\ndefine \"First hepatitis B dose from the primary series was administered\":\n  Encounter.\"One hepatitis B primary series dose was administered\""
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 6
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBEncounterElements"
            },
            {
              "url" : "name",
              "valueString" : "Two hepatitis B primary series doses were administered"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@input: Two hepatitis B primary series doses were administered\n@pseudocode: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\" = \"Primary series\") = 2\n@code: Two hepatitis B primary series doses were administered-131\n@decision: IMMZ.D2.DT.Hepatitis B.3 doses: 3-dose schedule (birth dose + 2 primary series doses), on-time start\n@decision: IMMZ.D2.DT.Hepatitis B.4 doses: 4-dose schedule (birth dose + 3 primary series doses), on-time start\n*/\ndefine \"Two hepatitis B primary series doses were administered\":\n  \"Number of Hepatitis B Primary Series Doses Administered\" = 2"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 7
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Second hepatitis B dose from the primary series was administered"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@complete: Second hepatitis B dose from the primary series was administered\n@pseudocode: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\"= \"Primary series\") = 2\n*/\ndefine \"Second hepatitis B dose from the primary series was administered\":\n  Encounter.\"Two hepatitis B primary series doses were administered\""
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 8
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBEncounterElements"
            },
            {
              "url" : "name",
              "valueString" : "Three hepatitis B primary series doses were administered"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@input: Three hepatitis B primary series doses were administered\n@pseudocode: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\" = \"Primary series\") = 3\n@code: Three hepatitis B primary series doses were administered-131\n@decision: IMMZ.D2.DT.Hepatitis B.3 doses: 3-dose schedule (birth dose + 2 primary series doses), on-time start\n@decision: IMMZ.D2.DT.Hepatitis B.4 doses: 4-dose schedule (birth dose + 3 primary series doses), on-time start\n*/\ndefine \"Three hepatitis B primary series doses were administered\":\n  \"Number of Hepatitis B Primary Series Doses Administered\" = 3"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 9
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Third hepatitis B dose from the primary series was administered. The primary series has been completed"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@complete: Third hepatitis B dose from the primary series was administered. The primary series has been completed\n@pseudocode: \"Completed the primary vaccination series\" = TRUE (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\")\n*/\ndefine \"Third hepatitis B dose from the primary series was administered. The primary series has been completed\":\n  Encounter.\"Three hepatitis B primary series doses were administered\""
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 10
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 1"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@output: Hepatitis B dose 1\n@description: Provision of hepatitis B dose 1\n@trigger: Child's birth\n@pseudo: \n@triggerDate: \"Date of birth\"\n*/\ndefine \"Hepatitis B dose 1\":\n  not \"First hepatitis B dose from the primary series was administered\"\n    and not \"Second hepatitis B dose from the primary series was administered\"\n    and not \"Third hepatitis B dose from the primary series was administered. The primary series has been completed\""
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 11
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
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          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 3"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@output: Hepatitis B dose 3\n@description: Provision of hepatitis B dose 3\n@trigger: Second hepatitis B dose from the primary series was administered\n@pseudo: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\"= \"Primary series\") = 2\n@triggerDate: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\")\n*/\ndefine \"Hepatitis B dose 3\":\n  \"Second hepatitis B dose from the primary series was administered\"\n    and not \"Third hepatitis B dose from the primary series was administered. The primary series has been completed\""
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 12
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          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
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          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 2"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@output: Hepatitis B dose 2\n@description: Provision of hepatitis B dose 2\n@trigger: First hepatitis B dose from the primary series was administered\n@pseudo: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\"= \"Primary series\") = 1\n@triggerDate: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\")\n*/\ndefine \"Hepatitis B dose 2\":\n  \"First hepatitis B dose from the primary series was administered\"\n    and not \"Second hepatitis B dose from the primary series was administered\"\n    and not \"Third hepatitis B dose from the primary series was administered. The primary series has been completed\""
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 13
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBEncounterElements"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B Doses Administered to Patient"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@internal: Hepatitis B containing Doses Administered to Patient\n*/\ndefine \"Hepatitis B Doses Administered to Patient\":\n  HepatitisBElements.\"Hepatitis B Doses Administered to Patient\".onOrBefore(Today)"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 14
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD2DTHepatitisBEncounterElements"
            },
            {
              "url" : "name",
              "valueString" : "Date of Latest Hepatitis B Dose"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@internal: Date of Latest Hepatitis B Dose\n*/\ndefine \"Date of Latest Hepatitis B Dose\":\n  date from start of \"Hepatitis B Doses Administered to Patient\".mostRecent().occurrence.toInterval()"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 15
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 2 Due Date"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@dynamicValue: Hepatitis B dose 2 Due Date\n@pseudocode: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\") + 4 weeks\n*/\ndefine \"Hepatitis B dose 2 Due Date\":\n  if \"Hepatitis B dose 2\" then Encounter.\"Date of Latest Hepatitis B Dose\" + 4 weeks\n  else null"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 16
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 2 Create"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@output: Hepatitis B dose 2 Create\n@create: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.\n*/\ndefine \"Hepatitis B dose 2 Create\":\n  if \"Hepatitis B dose 2\"\n  then 'The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.' + '\nDue Date: ' + ToString(\"Hepatitis B dose 2 Due Date\")\n  else ''"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 17
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 1 Due Date"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@dynamicValue: Hepatitis B dose 1 Due Date\n@pseudocode: \"Date of birth\" + Member States defined lower limit\n*/\ndefine \"Hepatitis B dose 1 Due Date\":\n  if \"Hepatitis B dose 1\" then Patient.birthDate + (Encounter.HepBLowerLimitWeeks * 1 weeks)\n  else null"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 18
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 1 Create"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@output: Hepatitis B dose 1 Create\n@create: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.\n*/\ndefine \"Hepatitis B dose 1 Create\":\n  if \"Hepatitis B dose 1\"\n  then 'The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.' + '\nDue Date: ' + ToString(\"Hepatitis B dose 1 Due Date\")\n  else ''"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 19
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 3 Due Date"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@dynamicValue: Hepatitis B dose 3 Due Date\n@pseudocode: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\") + 4 weeks\n*/\ndefine \"Hepatitis B dose 3 Due Date\":\n  if \"Hepatitis B dose 3\" then Encounter.\"Date of Latest Hepatitis B Dose\" + 4 weeks\n  else null"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 20
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZD18SHepatitisB4DosesLogic"
            },
            {
              "url" : "name",
              "valueString" : "Hepatitis B dose 3 Create"
            },
            {
              "url" : "statement",
              "valueString" : "/*\n@output: Hepatitis B dose 3 Create\n@create: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.\n*/\ndefine \"Hepatitis B dose 3 Create\":\n  if \"Hepatitis B dose 3\"\n  then 'The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.' + '\nDue Date: ' + ToString(\"Hepatitis B dose 3 Due Date\")\n  else ''"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 21
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZCommon"
            },
            {
              "url" : "name",
              "valueString" : "onOrBefore"
            },
            {
              "url" : "statement",
              "valueString" : "/**\n * @description: Gets immunizations on or before a date\n */\ndefine fluent function onOrBefore(immunizations List<Immunization>, beforeDate Date):\n  immunizations I where\n    I.occurrence.toInterval() same day or before beforeDate"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 22
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "IMMZCommon"
            },
            {
              "url" : "name",
              "valueString" : "seriesPrimary"
            },
            {
              "url" : "statement",
              "valueString" : "/**\n * @description: Gets the doses from the primary series\n */\ndefine fluent function seriesPrimary(immunizations List<Immunization>):\n  immunizations I where\n    exists( I.protocolApplied pa where pa.series = 'Primary series' )"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 23
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "FHIRHelpers"
            },
            {
              "url" : "name",
              "valueString" : "ToString"
            },
            {
              "url" : "statement",
              "valueString" : "define function ToString(value string): value.value"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 24
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "FHIRHelpers"
            },
            {
              "url" : "name",
              "valueString" : "ToString"
            },
            {
              "url" : "statement",
              "valueString" : "define function ToString(value ImmunizationStatus): value.value"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 25
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "FHIRHelpers"
            },
            {
              "url" : "name",
              "valueString" : "ToBoolean"
            },
            {
              "url" : "statement",
              "valueString" : "define function ToBoolean(value boolean): value.value"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 26
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "FHIRHelpers"
            },
            {
              "url" : "name",
              "valueString" : "ToConcept"
            },
            {
              "url" : "statement",
              "valueString" : "define function ToConcept(concept FHIR.CodeableConcept):\n    if concept is null then\n        null\n    else\n        System.Concept {\n            codes: concept.coding C return ToCode(C),\n            display: concept.text.value\n        }"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 27
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "FHIRHelpers"
            },
            {
              "url" : "name",
              "valueString" : "ToCode"
            },
            {
              "url" : "statement",
              "valueString" : "define function ToCode(coding FHIR.Coding):\n    if coding is null then\n        null\n    else\n        System.Code {\n          code: coding.code.value,\n          system: coding.system.value,\n          version: coding.version.value,\n          display: coding.display.value\n        }"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 28
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "WHOCommon"
            },
            {
              "url" : "name",
              "valueString" : "mostRecent"
            },
            {
              "url" : "statement",
              "valueString" : "define fluent function mostRecent(immunizations List<Immunization>):\n  Last(\n    immunizations I\n      sort by start of occurrence.toInterval()\n  )"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 29
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        },
        {
          "extension" : [
            {
              "url" : "libraryName",
              "valueString" : "FHIRHelpers"
            },
            {
              "url" : "name",
              "valueString" : "ToDate"
            },
            {
              "url" : "statement",
              "valueString" : "define function ToDate(value date): value.value"
            },
            {
              "url" : "displaySequence",
              "valueInteger" : 30
            }
          ],
          "url" : "http://hl7.org/fhir/StructureDefinition/cqf-logicDefinition"
        }
      ],
      "name" : "EffectiveDataRequirements",
      "status" : "active",
      "type" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/library-type",
            "code" : "module-definition"
          }
        ]
      },
      "relatedArtifact" : [
        {
          "type" : "depends-on",
          "display" : "FHIR model information",
          "resource" : "http://fhir.org/guides/cqf/common/Library/FHIR-ModelInfo|4.0.1"
        },
        {
          "type" : "depends-on",
          "display" : "Library Encounter",
          "resource" : "http://smart.who.int/immunizations/Library/IMMZD2DTHepatitisBEncounterElements"
        },
        {
          "type" : "depends-on",
          "display" : "Library Common",
          "resource" : "http://smart.who.int/immunizations/Library/IMMZCommon"
        },
        {
          "type" : "depends-on",
          "display" : "Library WC",
          "resource" : "http://smart.who.int/immunizations/Library/WHOCommon"
        },
        {
          "type" : "depends-on",
          "display" : "Library HepatitisBElements",
          "resource" : "http://smart.who.int/immunizations/Library/IMMZD2DTHepatitisBElements"
        },
        {
          "type" : "depends-on",
          "display" : "Library FHIRHelpers",
          "resource" : "http://fhir.org/guides/cqf/common/Library/FHIRHelpers|4.0.1"
        },
        {
          "type" : "depends-on",
          "display" : "Library Elements",
          "resource" : "http://smart.who.int/immunizations/Library/IMMZElements"
        },
        {
          "type" : "depends-on",
          "display" : "Library FHIRHelpers",
          "resource" : "http://fhir.org/guides/cqf/common/Library/FHIRHelpers|4.0.1"
        },
        {
          "type" : "depends-on",
          "display" : "Library Concepts",
          "resource" : "http://smart.who.int/immunizations/Library/IMMZConcepts"
        },
        {
          "type" : "depends-on",
          "display" : "Library WC",
          "resource" : "http://smart.who.int/immunizations/Library/WHOCommon"
        },
        {
          "type" : "depends-on",
          "display" : "Value set Hepatitis B-containing vaccines",
          "resource" : "http://smart.who.int/immunizations/ValueSet/IMMZ.Z.DE6"
        }
      ],
      "parameter" : [
        {
          "name" : "Today",
          "use" : "in",
          "min" : 0,
          "max" : "1",
          "type" : "date"
        },
        {
          "name" : "HepBLowerLimitWeeks",
          "use" : "in",
          "min" : 0,
          "max" : "1",
          "type" : "integer"
        },
        {
          "name" : "Hepatitis B dose 1",
          "use" : "out",
          "min" : 0,
          "max" : "1",
          "type" : "boolean"
        },
        {
          "name" : "Hepatitis B dose 3",
          "use" : "out",
          "min" : 0,
          "max" : "1",
          "type" : "boolean"
        },
        {
          "name" : "Hepatitis B dose 2",
          "use" : "out",
          "min" : 0,
          "max" : "1",
          "type" : "boolean"
        },
        {
          "name" : "Hepatitis B dose 2 Create",
          "use" : "out",
          "min" : 0,
          "max" : "1",
          "type" : "string"
        },
        {
          "name" : "Hepatitis B dose 1 Create",
          "use" : "out",
          "min" : 0,
          "max" : "1",
          "type" : "string"
        },
        {
          "name" : "Hepatitis B dose 3 Create",
          "use" : "out",
          "min" : 0,
          "max" : "1",
          "type" : "string"
        }
      ],
      "dataRequirement" : [
        {
          "type" : "Immunization",
          "profile" : [
            🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
          ],
          "mustSupport" : [
            "status",
            "isSubpotent"
          ]
        },
        {
          "type" : "Immunization",
          "profile" : [
            🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
          ],
          "mustSupport" : [
            "status",
            "isSubpotent",
            "vaccineCode"
          ]
        },
        {
          "type" : "Patient",
          "profile" : [
            🔗 "http://hl7.org/fhir/StructureDefinition/Patient"
          ]
        },
        {
          "type" : "Immunization",
          "profile" : [
            🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
          ],
          "mustSupport" : [
            "status",
            "isSubpotent",
            "vaccineCode"
          ]
        },
        {
          "type" : "Immunization",
          "profile" : [
            🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
          ],
          "mustSupport" : [
            "status",
            "isSubpotent",
            "vaccineCode"
          ]
        },
        {
          "type" : "Immunization",
          "profile" : [
            🔗 "http://hl7.org/fhir/StructureDefinition/Immunization"
          ],
          "mustSupport" : [
            "status",
            "isSubpotent",
            "vaccineCode"
          ]
        }
      ]
    }
  ],
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
      "valueCode" : "computable"
    },
    {
      "url" : "http://hl7.org/fhir/uv/crmi/StructureDefinition/crmi-effectiveDataRequirements",
      "valueCanonical" : "#effective-data-requirements"
    }
  ],
  "url" : "http://smart.who.int/immunizations/PlanDefinition/IMMZD18SHepatitisB4Doses",
  "version" : "0.2.0",
  "name" : "IMMZD18SHepatitisB4Doses",
  "title" : "IMMZ.D18.S.Hepatitis B.4-dose schedule",
  "type" : {
    "coding" : [
      {
        "system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
        "code" : "eca-rule"
      }
    ]
  },
  "status" : "draft",
  "experimental" : false,
  "date" : "2026-03-03T13:07:11+00:00",
  "publisher" : "WHO",
  "contact" : [
    {
      "name" : "WHO",
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://who.int"
        }
      ]
    }
  ],
  "description" : "IMMZ.D18.S.Hepatitis B.4-dose schedule\n4-dose schedule (birth dose + 3 primary series doses), on-time start",
  "relatedArtifact" : [
    {
      "type" : "citation",
      "citation" : "WHO recommendations for routine immunization - summary tables (January 2025)"
    }
  ],
  "library" : [
    🔗 "http://smart.who.int/immunizations/Library/IMMZD18SHepatitisB4DosesLogic"
  ],
  "action" : [
    {
      "title" : "Hepatitis B dose 1",
      "description" : "Provision of hepatitis B dose 1\nTrigger event: Child's birth\nTrigger pseudo: \nTrigger date: \"Date of birth\"\nCreate condition: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.",
      "condition" : [
        {
          "kind" : "applicability",
          "expression" : {
            "description" : "Hepatitis B dose 1",
            "language" : "text/cql-identifier",
            "expression" : "Hepatitis B dose 1"
          }
        }
      ],
      "definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
      "dynamicValue" : [
        {
          "path" : "status",
          "expression" : {
            "language" : "text/cql-expression",
            "expression" : "'active'"
          }
        },
        {
          "path" : "payload.contentString",
          "expression" : {
            "language" : "text/cql-identifier",
            "expression" : "Hepatitis B dose 1 Create"
          }
        },
        {
          "path" : "category.coding",
          "expression" : {
            "description" : "Category of communication",
            "language" : "text/cql-expression",
            "expression" : "Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"
          }
        },
        {
          "path" : "priority",
          "expression" : {
            "description" : "Alert priority",
            "language" : "text/cql-expression",
            "expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
          }
        }
      ]
    },
    {
      "title" : "Hepatitis B dose 2",
      "description" : "Provision of hepatitis B dose 2\nTrigger event: First hepatitis B dose from the primary series was administered\nTrigger pseudo: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\"= \"Primary series\") = 1\nTrigger date: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\")\nCreate condition: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.",
      "condition" : [
        {
          "kind" : "applicability",
          "expression" : {
            "description" : "Hepatitis B dose 2",
            "language" : "text/cql-identifier",
            "expression" : "Hepatitis B dose 2"
          }
        }
      ],
      "definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
      "dynamicValue" : [
        {
          "path" : "status",
          "expression" : {
            "language" : "text/cql-expression",
            "expression" : "'active'"
          }
        },
        {
          "path" : "payload.contentString",
          "expression" : {
            "language" : "text/cql-identifier",
            "expression" : "Hepatitis B dose 2 Create"
          }
        },
        {
          "path" : "category.coding",
          "expression" : {
            "description" : "Category of communication",
            "language" : "text/cql-expression",
            "expression" : "Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"
          }
        },
        {
          "path" : "priority",
          "expression" : {
            "description" : "Alert priority",
            "language" : "text/cql-expression",
            "expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
          }
        }
      ]
    },
    {
      "title" : "Hepatitis B dose 3",
      "description" : "Provision of hepatitis B dose 3\nTrigger event: Second hepatitis B dose from the primary series was administered\nTrigger pseudo: Count of vaccines administered (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\" and \"Type of dose\"= \"Primary series\") = 2\nTrigger date: Latest \"Date and time of vaccination\" (where \"Vaccine type\" = \"Hepatitis B-containing vaccines\")\nCreate condition: The following option is considered appropriate: 4 doses, where a monovalent birth dose is followed by 3 (monovalent or combined vaccine) doses, usually given with other routine infant vaccines; the additional dose does not cause any harm. The interval between doses should be at least 4 weeks.",
      "condition" : [
        {
          "kind" : "applicability",
          "expression" : {
            "description" : "Hepatitis B dose 3",
            "language" : "text/cql-identifier",
            "expression" : "Hepatitis B dose 3"
          }
        }
      ],
      "definitionCanonical" : "http://smart.who.int/immunizations/ActivityDefinition/IMMZD2DTCR",
      "dynamicValue" : [
        {
          "path" : "status",
          "expression" : {
            "language" : "text/cql-expression",
            "expression" : "'active'"
          }
        },
        {
          "path" : "payload.contentString",
          "expression" : {
            "language" : "text/cql-identifier",
            "expression" : "Hepatitis B dose 3 Create"
          }
        },
        {
          "path" : "category.coding",
          "expression" : {
            "description" : "Category of communication",
            "language" : "text/cql-expression",
            "expression" : "Code { system: 'http://terminology.hl7.org/CodeSystem/communication-category', code: 'alert' }"
          }
        },
        {
          "path" : "priority",
          "expression" : {
            "description" : "Alert priority",
            "language" : "text/cql-expression",
            "expression" : "Code { system: 'http://hl7.org/fhir/request-priority', code: 'routine' }"
          }
        }
      ]
    }
  ]
}